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Phosphoproteomics of three exercise modalities identifies canonical signaling and C18ORF25 as an AMPK substrate regulating skeletal muscle function.
Blazev R, Carl CS, Ng YK, Molendijk J, Voldstedlund CT, Zhao Y, Xiao D, Kueh AJ, Miotto PM, Haynes VR, Hardee JP, Chung JD, McNamara JW, Qian H, Gregorevic P, Oakhill JS, Herold MJ, Jensen TE, Lisowski L, Lynch GS, Dodd GT, Watt MJ, Yang P, Kiens B, Richter EA, Parker BL. Blazev R, et al. Among authors: haynes vr. Cell Metab. 2022 Oct 4;34(10):1561-1577.e9. doi: 10.1016/j.cmet.2022.07.003. Epub 2022 Jul 25. Cell Metab. 2022. PMID: 35882232 Free article.
Mas Receptor Activation Slows Tumor Growth and Attenuates Muscle Wasting in Cancer.
Murphy KT, Hossain MI, Swiderski K, Chee A, Naim T, Trieu J, Haynes V, Read SJ, Stapleton DI, Judge SM, Trevino JG, Judge AR, Lynch GS. Murphy KT, et al. Cancer Res. 2019 Feb 15;79(4):706-719. doi: 10.1158/0008-5472.CAN-18-1207. Epub 2018 Nov 12. Cancer Res. 2019. PMID: 30420474 Free PMC article.
A Neural basis for Octanoic acid regulation of energy balance.
Haynes VR, Michael NJ, van den Top M, Zhao FY, Brown RD, De Souza D, Dodd GT, Spanswick D, Watt MJ. Haynes VR, et al. Mol Metab. 2020 Apr;34:54-71. doi: 10.1016/j.molmet.2020.01.002. Epub 2020 Jan 9. Mol Metab. 2020. PMID: 32180560 Free PMC article.
Suppressing fatty acid uptake has therapeutic effects in preclinical models of prostate cancer.
Watt MJ, Clark AK, Selth LA, Haynes VR, Lister N, Rebello R, Porter LH, Niranjan B, Whitby ST, Lo J, Huang C, Schittenhelm RB, Anderson KE, Furic L, Wijayaratne PR, Matzaris M, Montgomery MK, Papargiris M, Norden S, Febbraio M, Risbridger GP, Frydenberg M, Nomura DK, Taylor RA. Watt MJ, et al. Among authors: haynes vr. Sci Transl Med. 2019 Feb 6;11(478):eaau5758. doi: 10.1126/scitranslmed.aau5758. Sci Transl Med. 2019. PMID: 30728288
Two regulatory T cell populations in the visceral adipose tissue shape systemic metabolism.
Torres SV, Man K, Elmzzahi T, Malko D, Chisanga D, Liao Y, Prout M, Abbott CA, Tang A, Wu J, Becker M, Mason T, Haynes V, Tsui C, Shakiba MH, Hamada D, Britt K, Groom JR, McColl SR, Shi W, Watt MJ, Le Gros G, Pal B, Beyer M, Vasanthakumar A, Kallies A. Torres SV, et al. Nat Immunol. 2024 Mar;25(3):496-511. doi: 10.1038/s41590-024-01753-9. Epub 2024 Feb 14. Nat Immunol. 2024. PMID: 38356058