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Page 1
Cooperative allostery and structural dynamics of streptavidin at cryogenic- and ambient-temperature.
Ayan E, Yuksel B, Destan E, Ertem FB, Yildirim G, Eren M, Yefanov OM, Barty A, Tolstikova A, Ketawala GK, Botha S, Dao EH, Hayes B, Liang M, Seaberg MH, Hunter MS, Batyuk A, Mariani V, Su Z, Poitevin F, Yoon CH, Kupitz C, Cohen A, Doukov T, Sierra RG, Dağ Ç, DeMirci H. Ayan E, et al. Among authors: hayes b. Commun Biol. 2022 Jan 20;5(1):73. doi: 10.1038/s42003-021-02903-7. Commun Biol. 2022. PMID: 35058563 Free PMC article.
Concentric-flow electrokinetic injector enables serial crystallography of ribosome and photosystem II.
Sierra RG, Gati C, Laksmono H, Dao EH, Gul S, Fuller F, Kern J, Chatterjee R, Ibrahim M, Brewster AS, Young ID, Michels-Clark T, Aquila A, Liang M, Hunter MS, Koglin JE, Boutet S, Junco EA, Hayes B, Bogan MJ, Hampton CY, Puglisi EV, Sauter NK, Stan CA, Zouni A, Yano J, Yachandra VK, Soltis SM, Puglisi JD, DeMirci H. Sierra RG, et al. Among authors: hayes b. Nat Methods. 2016 Jan;13(1):59-62. doi: 10.1038/nmeth.3667. Epub 2015 Nov 30. Nat Methods. 2016. PMID: 26619013 Free PMC article.
Se-SAD serial femtosecond crystallography datasets from selenobiotinyl-streptavidin.
Yoon CH, DeMirci H, Sierra RG, Dao EH, Ahmadi R, Aksit F, Aquila AL, Batyuk A, Ciftci H, Guillet S, Hayes MJ, Hayes B, Lane TJ, Liang M, Lundström U, Koglin JE, Mgbam P, Rao Y, Rendahl T, Rodriguez E, Zhang L, Wakatsuki S, Boutet S, Holton JM, Hunter MS. Yoon CH, et al. Among authors: hayes b, hayes mj. Sci Data. 2017 Apr 25;4:170055. doi: 10.1038/sdata.2017.55. Sci Data. 2017. PMID: 28440794 Free PMC article.
Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature.
O'Sullivan ME, Poitevin F, Sierra RG, Gati C, Dao EH, Rao Y, Aksit F, Ciftci H, Corsepius N, Greenhouse R, Hayes B, Hunter MS, Liang M, McGurk A, Mbgam P, Obrinsky T, Pardo-Avila F, Seaberg MH, Cheng AG, Ricci AJ, DeMirci H. O'Sullivan ME, et al. Among authors: hayes b. Nucleic Acids Res. 2018 Oct 12;46(18):9793-9804. doi: 10.1093/nar/gky693. Nucleic Acids Res. 2018. PMID: 30113694 Free PMC article.
Structure of the 30S ribosomal decoding complex at ambient temperature.
Dao EH, Poitevin F, Sierra RG, Gati C, Rao Y, Ciftci HI, Akşit F, McGurk A, Obrinski T, Mgbam P, Hayes B, De Lichtenberg C, Pardo-Avila F, Corsepius N, Zhang L, Seaberg MH, Hunter MS, Liang M, Koglin JE, Wakatsuki S, Demirci H. Dao EH, et al. Among authors: hayes b. RNA. 2018 Dec;24(12):1667-1676. doi: 10.1261/rna.067660.118. Epub 2018 Aug 23. RNA. 2018. PMID: 30139800 Free PMC article.
The Macromolecular Femtosecond Crystallography Instrument at the Linac Coherent Light Source.
Sierra RG, Batyuk A, Sun Z, Aquila A, Hunter MS, Lane TJ, Liang M, Yoon CH, Alonso-Mori R, Armenta R, Castagna JC, Hollenbeck M, Osier TO, Hayes M, Aldrich J, Curtis R, Koglin JE, Rendahl T, Rodriguez E, Carbajo S, Guillet S, Paul R, Hart P, Nakahara K, Carini G, DeMirci H, Dao EH, Hayes BM, Rao YP, Chollet M, Feng Y, Fuller FD, Kupitz C, Sato T, Seaberg MH, Song S, van Driel TB, Yavas H, Zhu D, Cohen AE, Wakatsuki S, Boutet S. Sierra RG, et al. Among authors: hayes bm, hayes m. J Synchrotron Radiat. 2019 Mar 1;26(Pt 2):346-357. doi: 10.1107/S1600577519001577. Epub 2019 Feb 22. J Synchrotron Radiat. 2019. PMID: 30855242 Free PMC article.
Mix-and-inject XFEL crystallography reveals gated conformational dynamics during enzyme catalysis.
Dasgupta M, Budday D, de Oliveira SHP, Madzelan P, Marchany-Rivera D, Seravalli J, Hayes B, Sierra RG, Boutet S, Hunter MS, Alonso-Mori R, Batyuk A, Wierman J, Lyubimov A, Brewster AS, Sauter NK, Applegate GA, Tiwari VK, Berkowitz DB, Thompson MC, Cohen AE, Fraser JS, Wall ME, van den Bedem H, Wilson MA. Dasgupta M, et al. Among authors: hayes b. Proc Natl Acad Sci U S A. 2019 Dec 17;116(51):25634-25640. doi: 10.1073/pnas.1901864116. Epub 2019 Dec 4. Proc Natl Acad Sci U S A. 2019. PMID: 31801874 Free PMC article.
Near-physiological-temperature serial crystallography reveals conformations of SARS-CoV-2 main protease active site for improved drug repurposing.
Durdagi S, Dağ Ç, Dogan B, Yigin M, Avsar T, Buyukdag C, Erol I, Ertem FB, Calis S, Yildirim G, Orhan MD, Guven O, Aksoydan B, Destan E, Sahin K, Besler SO, Oktay L, Shafiei A, Tolu I, Ayan E, Yuksel B, Peksen AB, Gocenler O, Yucel AD, Can O, Ozabrahamyan S, Olkan A, Erdemoglu E, Aksit F, Tanisali G, Yefanov OM, Barty A, Tolstikova A, Ketawala GK, Botha S, Dao EH, Hayes B, Liang M, Seaberg MH, Hunter MS, Batyuk A, Mariani V, Su Z, Poitevin F, Yoon CH, Kupitz C, Sierra RG, Snell EH, DeMirci H. Durdagi S, et al. Among authors: hayes b. Structure. 2021 Dec 2;29(12):1382-1396.e6. doi: 10.1016/j.str.2021.07.007. Epub 2021 Aug 16. Structure. 2021. PMID: 34403647 Free PMC article.
Chemical crystallography by serial femtosecond X-ray diffraction.
Schriber EA, Paley DW, Bolotovsky R, Rosenberg DJ, Sierra RG, Aquila A, Mendez D, Poitevin F, Blaschke JP, Bhowmick A, Kelly RP, Hunter M, Hayes B, Popple DC, Yeung M, Pareja-Rivera C, Lisova S, Tono K, Sugahara M, Owada S, Kuykendall T, Yao K, Schuck PJ, Solis-Ibarra D, Sauter NK, Brewster AS, Hohman JN. Schriber EA, et al. Among authors: hayes b. Nature. 2022 Jan;601(7893):360-365. doi: 10.1038/s41586-021-04218-3. Epub 2022 Jan 19. Nature. 2022. PMID: 35046599 Free PMC article.
Protocol for structure determination of SARS-CoV-2 main protease at near-physiological-temperature by serial femtosecond crystallography.
Ertem FB, Guven O, Buyukdag C, Gocenler O, Ayan E, Yuksel B, Gul M, Usta G, Cakılkaya B, Johnson JA, Dao EH, Su Z, Poitevin F, Yoon CH, Kupitz C, Hayes B, Liang M, Hunter MS, Batyuk A, Sierra RG, Ketawala G, Botha S, Dağ Ç, DeMirci H. Ertem FB, et al. Among authors: hayes b. STAR Protoc. 2022 Jan 24;3(1):101158. doi: 10.1016/j.xpro.2022.101158. eCollection 2022 Mar 18. STAR Protoc. 2022. PMID: 35194584 Free PMC article.
1,053 results