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Broad-Spectrum Antiviral Activity of 3'-Deoxy-3'-Fluoroadenosine against Emerging Flaviviruses.
Eyer L, Svoboda P, Balvan J, Vičar T, Raudenská M, Štefánik M, Haviernik J, Huvarová I, Straková P, Rudolf I, Hubálek Z, Seley-Radtke K, de Clercq E, Růžek D. Eyer L, et al. Among authors: haviernik j. Antimicrob Agents Chemother. 2021 Jan 20;65(2):e01522-20. doi: 10.1128/AAC.01522-20. Print 2021 Jan 20. Antimicrob Agents Chemother. 2021. PMID: 33229424 Free PMC article.
Escape of Tick-Borne Flavivirus from 2'-C-Methylated Nucleoside Antivirals Is Mediated by a Single Conservative Mutation in NS5 That Has a Dramatic Effect on Viral Fitness.
Eyer L, Kondo H, Zouharova D, Hirano M, Valdés JJ, Muto M, Kastl T, Kobayashi S, Haviernik J, Igarashi M, Kariwa H, Vaculovicova M, Cerny J, Kizek R, Kröger A, Lienenklaus S, Dejmek M, Nencka R, Palus M, Salat J, De Clercq E, Yoshii K, Ruzek D. Eyer L, et al. Among authors: haviernik j. J Virol. 2017 Oct 13;91(21):e01028-17. doi: 10.1128/JVI.01028-17. Print 2017 Nov 1. J Virol. 2017. PMID: 28814513 Free PMC article.
An E460D Substitution in the NS5 Protein of Tick-Borne Encephalitis Virus Confers Resistance to the Inhibitor Galidesivir (BCX4430) and Also Attenuates the Virus for Mice.
Eyer L, Nougairède A, Uhlířová M, Driouich JS, Zouharová D, Valdés JJ, Haviernik J, Gould EA, De Clercq E, de Lamballerie X, Ruzek D. Eyer L, et al. Among authors: haviernik j. J Virol. 2019 Jul 30;93(16):e00367-19. doi: 10.1128/JVI.00367-19. Print 2019 Aug 15. J Virol. 2019. PMID: 31142664 Free PMC article.
Tick-Borne Encephalitis Virus Vaccines Contain Non-Structural Protein 1 Antigen and may Elicit NS1-Specific Antibody Responses in Vaccinated Individuals.
Salat J, Mikulasek K, Larralde O, Pokorna Formanova P, Chrdle A, Haviernik J, Elsterova J, Teislerova D, Palus M, Eyer L, Zdrahal Z, Petrik J, Ruzek D. Salat J, et al. Among authors: haviernik j. Vaccines (Basel). 2020 Feb 12;8(1):81. doi: 10.3390/vaccines8010081. Vaccines (Basel). 2020. PMID: 32059489 Free PMC article.
Development and characterization of recombinant tick-borne encephalitis virus expressing mCherry reporter protein: A new tool for high-throughput screening of antiviral compounds, and neutralizing antibody assays.
Haviernik J, Eyer L, Yoshii K, Kobayashi S, Cerny J, Nougairède A, Driouich JS, Volf J, Palus M, de Lamballerie X, Gould EA, Ruzek D. Haviernik J, et al. Antiviral Res. 2021 Jan;185:104968. doi: 10.1016/j.antiviral.2020.104968. Epub 2020 Nov 4. Antiviral Res. 2021. PMID: 33157129
Bispecific IgG neutralizes SARS-CoV-2 variants and prevents escape in mice.
De Gasparo R, Pedotti M, Simonelli L, Nickl P, Muecksch F, Cassaniti I, Percivalle E, Lorenzi JCC, Mazzola F, Magrì D, Michalcikova T, Haviernik J, Honig V, Mrazkova B, Polakova N, Fortova A, Tureckova J, Iatsiuk V, Di Girolamo S, Palus M, Zudova D, Bednar P, Bukova I, Bianchini F, Mehn D, Nencka R, Strakova P, Pavlis O, Rozman J, Gioria S, Sammartino JC, Giardina F, Gaiarsa S, Pan-Hammarström Q, Barnes CO, Bjorkman PJ, Calzolai L, Piralla A, Baldanti F, Nussenzweig MC, Bieniasz PD, Hatziioannou T, Prochazka J, Sedlacek R, Robbiani DF, Ruzek D, Varani L. De Gasparo R, et al. Among authors: haviernik j. Nature. 2021 May;593(7859):424-428. doi: 10.1038/s41586-021-03461-y. Epub 2021 Mar 25. Nature. 2021. PMID: 33767445
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