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Loss of Pax5 Exploits Sca1-BCR-ABLp190 Susceptibility to Confer the Metabolic Shift Essential for pB-ALL.
Martín-Lorenzo A, Auer F, Chan LN, García-Ramírez I, González-Herrero I, Rodríguez-Hernández G, Bartenhagen C, Dugas M, Gombert M, Ginzel S, Blanco O, Orfao A, Alonso-López D, Rivas JL, García-Cenador MB, García-Criado FJ, Müschen M, Sánchez-García I, Borkhardt A, Vicente-Dueñas C, Hauer J. Martín-Lorenzo A, et al. Among authors: hauer j. Cancer Res. 2018 May 15;78(10):2669-2679. doi: 10.1158/0008-5472.CAN-17-3262. Epub 2018 Feb 28. Cancer Res. 2018. PMID: 29490943 Free PMC article.
Anti-leukaemic activity of a novel haploidentical-transplantation approach employing unmanipulated bone marrow followed by CD6-depleted peripheral blood stem cells in children with refractory/relapsed acute leukaemia.
Schuster FR, Meisel R, Führer M, Reuther S, Hauer J, Tischer J, Feuchtinger T, Laws HJ, Kolb HJ, Borkhardt A. Schuster FR, et al. Among authors: hauer j. Br J Haematol. 2013 Sep;162(6):802-7. doi: 10.1111/bjh.12455. Epub 2013 Jul 6. Br J Haematol. 2013. PMID: 23829632 Free article.
Inherited susceptibility to pre B-ALL caused by germline transmission of PAX5 c.547G>A.
Auer F, Rüschendorf F, Gombert M, Husemann P, Ginzel S, Izraeli S, Harit M, Weintraub M, Weinstein OY, Lerer I, Stepensky P, Borkhardt A, Hauer J. Auer F, et al. Among authors: hauer j. Leukemia. 2014 May;28(5):1136-8. doi: 10.1038/leu.2013.363. Epub 2013 Nov 29. Leukemia. 2014. PMID: 24287434 No abstract available.
Infection Exposure is a Causal Factor in B-cell Precursor Acute Lymphoblastic Leukemia as a Result of Pax5-Inherited Susceptibility.
Martín-Lorenzo A, Hauer J, Vicente-Dueñas C, Auer F, González-Herrero I, García-Ramírez I, Ginzel S, Thiele R, Constantinescu SN, Bartenhagen C, Dugas M, Gombert M, Schäfer D, Blanco O, Mayado A, Orfao A, Alonso-López D, Rivas Jde L, Cobaleda C, García-Cenador MB, García-Criado FJ, Sánchez-García I, Borkhardt A. Martín-Lorenzo A, et al. Among authors: hauer j. Cancer Discov. 2015 Dec;5(12):1328-43. doi: 10.1158/2159-8290.CD-15-0892. Epub 2015 Sep 25. Cancer Discov. 2015. PMID: 26408659
Infection causes childhood leukemia.
Hauer J, Martín-Lorenzo A, Sánchez-García I. Hauer J, et al. Aging (Albany NY). 2015 Sep;7(9):607-8. doi: 10.18632/aging.100815. Aging (Albany NY). 2015. PMID: 26412458 Free PMC article. No abstract available.
GEMMs addressing Pax5 loss-of-function in childhood pB-ALL.
Auer F, Ingenhag D, Bhatia S, Enczmann J, Cobaleda C, Sanchez-Garcia I, Borkhardt A, Hauer J. Auer F, et al. Among authors: hauer j. Eur J Med Genet. 2016 Mar;59(3):166-72. doi: 10.1016/j.ejmg.2015.11.009. Epub 2015 Nov 26. Eur J Med Genet. 2016. PMID: 26626503 Review.
224 results