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Antibody titers against SARS-CoV-2 decline, but do not disappear for several months.
Yamayoshi S, Yasuhara A, Ito M, Akasaka O, Nakamura M, Nakachi I, Koga M, Mitamura K, Yagi K, Maeda K, Kato H, Nojima M, Pattinson D, Ogura T, Baba R, Fujita K, Nagai H, Yamamoto S, Saito M, Adachi E, Ochi J, Hattori SI, Suzuki T, Miyazato Y, Chiba S, Okuda M, Murakami J, Hamabata T, Iwatsuki-Horimoto K, Nakajima H, Mitsuya H, Omagari N, Sugaya N, Yotsuyanagi H, Kawaoka Y. Yamayoshi S, et al. Among authors: hattori si. EClinicalMedicine. 2021 Feb;32:100734. doi: 10.1016/j.eclinm.2021.100734. Epub 2021 Feb 11. EClinicalMedicine. 2021. PMID: 33589882 Free PMC article.
Design and Synthesis of Potent HIV-1 Protease Inhibitors Containing Bicyclic Oxazolidinone Scaffold as the P2 Ligands: Structure-Activity Studies and Biological and X-ray Structural Studies.
Ghosh AK, Williams JN, Ho RY, Simpson HM, Hattori SI, Hayashi H, Agniswamy J, Wang YF, Weber IT, Mitsuya H. Ghosh AK, et al. Among authors: hattori si. J Med Chem. 2018 Nov 8;61(21):9722-9737. doi: 10.1021/acs.jmedchem.8b01227. Epub 2018 Oct 24. J Med Chem. 2018. PMID: 30354121 Free PMC article.
Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors.
Yasutake Y, Hattori SI, Tamura N, Matsuda K, Kohgo S, Maeda K, Mitsuya H. Yasutake Y, et al. Among authors: hattori si. Biochem Biophys Res Commun. 2019 Feb 19;509(4):943-948. doi: 10.1016/j.bbrc.2019.01.026. Epub 2019 Jan 14. Biochem Biophys Res Commun. 2019. PMID: 30648556
Transmission of SARS-CoV-2 in Domestic Cats.
Halfmann PJ, Hatta M, Chiba S, Maemura T, Fan S, Takeda M, Kinoshita N, Hattori SI, Sakai-Tagawa Y, Iwatsuki-Horimoto K, Imai M, Kawaoka Y. Halfmann PJ, et al. Among authors: hattori si. N Engl J Med. 2020 Aug 6;383(6):592-594. doi: 10.1056/NEJMc2013400. Epub 2020 May 13. N Engl J Med. 2020. PMID: 32402157 Free PMC article. No abstract available.
Syrian hamsters as a small animal model for SARS-CoV-2 infection and countermeasure development.
Imai M, Iwatsuki-Horimoto K, Hatta M, Loeber S, Halfmann PJ, Nakajima N, Watanabe T, Ujie M, Takahashi K, Ito M, Yamada S, Fan S, Chiba S, Kuroda M, Guan L, Takada K, Armbrust T, Balogh A, Furusawa Y, Okuda M, Ueki H, Yasuhara A, Sakai-Tagawa Y, Lopes TJS, Kiso M, Yamayoshi S, Kinoshita N, Ohmagari N, Hattori SI, Takeda M, Mitsuya H, Krammer F, Suzuki T, Kawaoka Y. Imai M, et al. Among authors: hattori si. Proc Natl Acad Sci U S A. 2020 Jul 14;117(28):16587-16595. doi: 10.1073/pnas.2009799117. Epub 2020 Jun 22. Proc Natl Acad Sci U S A. 2020. PMID: 32571934 Free PMC article.
GRL-0920, an Indole Chloropyridinyl Ester, Completely Blocks SARS-CoV-2 Infection.
Hattori SI, Higshi-Kuwata N, Raghavaiah J, Das D, Bulut H, Davis DA, Takamatsu Y, Matsuda K, Takamune N, Kishimoto N, Okamura T, Misumi S, Yarchoan R, Maeda K, Ghosh AK, Mitsuya H. Hattori SI, et al. mBio. 2020 Aug 20;11(4):e01833-20. doi: 10.1128/mBio.01833-20. mBio. 2020. PMID: 32820005 Free PMC article.
51 results