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Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders.
Johmura Y, Yamanaka T, Omori S, Wang TW, Sugiura Y, Matsumoto M, Suzuki N, Kumamoto S, Yamaguchi K, Hatakeyama S, Takami T, Yamaguchi R, Shimizu E, Ikeda K, Okahashi N, Mikawa R, Suematsu M, Arita M, Sugimoto M, Nakayama KI, Furukawa Y, Imoto S, Nakanishi M. Johmura Y, et al. Among authors: hatakeyama s. Science. 2021 Jan 15;371(6526):265-270. doi: 10.1126/science.abb5916. Science. 2021. PMID: 33446552
Detection of APC mosaicism by next-generation sequencing in an FAP patient.
Yamaguchi K, Komura M, Yamaguchi R, Imoto S, Shimizu E, Kasuya S, Shibuya T, Hatakeyama S, Takahashi N, Ikenoue T, Hata K, Tsurita G, Shinozaki M, Suzuki Y, Sugano S, Miyano S, Furukawa Y. Yamaguchi K, et al. Among authors: hatakeyama s. J Hum Genet. 2015 May;60(5):227-31. doi: 10.1038/jhg.2015.14. Epub 2015 Feb 26. J Hum Genet. 2015. PMID: 25716913
Attenuated familial adenomatous polyposis with desmoids caused by an APC mutation.
Ikenoue T, Yamaguchi K, Komura M, Imoto S, Yamaguchi R, Shimizu E, Kasuya S, Shibuya T, Hatakeyama S, Miyano S, Furukawa Y. Ikenoue T, et al. Among authors: hatakeyama s. Hum Genome Var. 2015 Mar 26;2:15011. doi: 10.1038/hgv.2015.11. eCollection 2015. Hum Genome Var. 2015. PMID: 27081525 Free PMC article.
Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo.
Omori S, Wang TW, Johmura Y, Kanai T, Nakano Y, Kido T, Susaki EA, Nakajima T, Shichino S, Ueha S, Ozawa M, Yokote K, Kumamoto S, Nishiyama A, Sakamoto T, Yamaguchi K, Hatakeyama S, Shimizu E, Katayama K, Yamada Y, Yamazaki S, Iwasaki K, Miyoshi C, Funato H, Yanagisawa M, Ueno H, Imoto S, Furukawa Y, Yoshida N, Matsushima K, Ueda HR, Miyajima A, Nakanishi M. Omori S, et al. Among authors: hatakeyama s. Cell Metab. 2020 Nov 3;32(5):814-828.e6. doi: 10.1016/j.cmet.2020.09.006. Epub 2020 Sep 18. Cell Metab. 2020. PMID: 32949498 Free article.
Comprehensive molecular analysis of genomic profiles and PD-L1 expression in lung adenocarcinoma with a high-grade fetal adenocarcinoma component.
Suzuki M, Kasajima R, Yokose T, Ito H, Shimizu E, Hatakeyama S, Yokoyama K, Yamaguchi R, Furukawa Y, Miyano S, Imoto S, Yoshioka E, Washimi K, Okubo Y, Kawachi K, Sato S, Miyagi Y. Suzuki M, et al. Among authors: hatakeyama s. Transl Lung Cancer Res. 2021 Mar;10(3):1292-1304. doi: 10.21037/tlcr-20-1158. Transl Lung Cancer Res. 2021. PMID: 33889510 Free PMC article.
Application of targeted nanopore sequencing for the screening and determination of structural variants in patients with Lynch syndrome.
Yamaguchi K, Kasajima R, Takane K, Hatakeyama S, Shimizu E, Yamaguchi R, Katayama K, Arai M, Ishioka C, Iwama T, Kaneko S, Matsubara N, Moriya Y, Nomizu T, Sugano K, Tamura K, Tomita N, Yoshida T, Sugihara K, Nakamura Y, Miyano S, Imoto S, Furukawa Y, Ikenoue T. Yamaguchi K, et al. Among authors: hatakeyama s. J Hum Genet. 2021 Nov;66(11):1053-1060. doi: 10.1038/s10038-021-00927-9. Epub 2021 May 6. J Hum Genet. 2021. PMID: 33958709
Blocking PD-L1-PD-1 improves senescence surveillance and ageing phenotypes.
Wang TW, Johmura Y, Suzuki N, Omori S, Migita T, Yamaguchi K, Hatakeyama S, Yamazaki S, Shimizu E, Imoto S, Furukawa Y, Yoshimura A, Nakanishi M. Wang TW, et al. Among authors: hatakeyama s. Nature. 2022 Nov;611(7935):358-364. doi: 10.1038/s41586-022-05388-4. Epub 2022 Nov 2. Nature. 2022. PMID: 36323784
1,077 results