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Extracellular proteostasis prevents aggregation during pathogenic attack.
Gallotta I, Sandhu A, Peters M, Haslbeck M, Jung R, Agilkaya S, Blersch JL, Rödelsperger C, Röseler W, Huang C, Sommer RJ, David DC. Gallotta I, et al. Among authors: haslbeck m. Nature. 2020 Aug;584(7821):410-414. doi: 10.1038/s41586-020-2461-z. Epub 2020 Jul 8. Nature. 2020. PMID: 32641833
The molecular basis of chaperone-mediated interleukin 23 assembly control.
Meier S, Bohnacker S, Klose CJ, Lopez A, Choe CA, Schmid PWN, Bloemeke N, Rührnößl F, Haslbeck M, Bieren JE, Sattler M, Huang PS, Feige MJ. Meier S, et al. Among authors: haslbeck m. Nat Commun. 2019 Sep 11;10(1):4121. doi: 10.1038/s41467-019-12006-x. Nat Commun. 2019. PMID: 31511508 Free PMC article.
Imbalances in the eye lens proteome are linked to cataract formation.
Schmid PWN, Lim NCH, Peters C, Back KC, Bourgeois B, Pirolt F, Richter B, Peschek J, Puk O, Amarie OV, Dalke C, Haslbeck M, Weinkauf S, Madl T, Graw J, Buchner J. Schmid PWN, et al. Among authors: haslbeck m. Nat Struct Mol Biol. 2021 Feb;28(2):143-151. doi: 10.1038/s41594-020-00543-9. Epub 2021 Jan 11. Nat Struct Mol Biol. 2021. PMID: 33432246
Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly.
Taş K, Volta BD, Lindner C, El Bounkari O, Hille K, Tian Y, Puig-Bosch X, Ballmann M, Hornung S, Ortner M, Prem S, Meier L, Rammes G, Haslbeck M, Weber C, Megens RTA, Bernhagen J, Kapurniotu A. Taş K, et al. Among authors: haslbeck m. Nat Commun. 2022 Aug 25;13(1):5004. doi: 10.1038/s41467-022-32688-0. Nat Commun. 2022. PMID: 36008417 Free PMC article.
The structure and oxidation of the eye lens chaperone αA-crystallin.
Kaiser CJO, Peters C, Schmid PWN, Stavropoulou M, Zou J, Dahiya V, Mymrikov EV, Rockel B, Asami S, Haslbeck M, Rappsilber J, Reif B, Zacharias M, Buchner J, Weinkauf S. Kaiser CJO, et al. Among authors: haslbeck m. Nat Struct Mol Biol. 2019 Dec;26(12):1141-1150. doi: 10.1038/s41594-019-0332-9. Epub 2019 Dec 2. Nat Struct Mol Biol. 2019. PMID: 31792453 Free PMC article.
200 results