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SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Hartmann J, Bajaj T, Otten J, Klengel C, Ebert T, Gellner AK, Junglas E, Hafner K, Anderzhanova EA, Tang F, Missig G, Rexrode L, Trussell DT, Li KX, Pöhlmann ML, Mackert S, Geiger TM, Heinz DE, Lardenoije R, Dedic N, McCullough KM, Próchnicki T, Rhomberg T, Martinelli S, Payton A, Robinson AC, Stein V, Latz E, Carlezon WA Jr, Hausch F, Schmidt MV, Murgatroyd C, Berretta S, Klengel T, Pantazopoulos H, Ressler KJ, Gassen NC. Hartmann J, et al. Nat Commun. 2024 Mar 25;15(1):2635. doi: 10.1038/s41467-024-46953-x. Nat Commun. 2024. PMID: 38528004 Free PMC article.
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion.
Martinelli S, Anderzhanova EA, Bajaj T, Wiechmann S, Dethloff F, Weckmann K, Heinz DE, Ebert T, Hartmann J, Geiger TM, Döngi M, Hafner K, Pöhlmann ML, Jollans L, Philipsen A, Schmidt SV, Schmidt U, Maccarrone G, Stein V, Hausch F, Turck CW, Schmidt MV, Gellner AK, Kuster B, Gassen NC. Martinelli S, et al. Among authors: hartmann j. Nat Commun. 2021 Jul 30;12(1):4643. doi: 10.1038/s41467-021-24810-5. Nat Commun. 2021. PMID: 34330919 Free PMC article.
Mineralocorticoid receptors dampen glucocorticoid receptor sensitivity to stress via regulation of FKBP5.
Hartmann J, Bajaj T, Klengel C, Chatzinakos C, Ebert T, Dedic N, McCullough KM, Lardenoije R, Joëls M, Meijer OC, McCann KE, Dudek SM, Sarabdjitsingh RA, Daskalakis NP, Klengel T, Gassen NC, Schmidt MV, Ressler KJ. Hartmann J, et al. Cell Rep. 2021 Jun 1;35(9):109185. doi: 10.1016/j.celrep.2021.109185. Cell Rep. 2021. PMID: 34077736 Free PMC article.
SKA2 regulated hyperactive secretory autophagy drives neuroinflammation-induced neurodegeneration.
Hartmann J, Bajaj T, Otten J, Klengel C, Gellner AK, Junglas E, Hafner K, Anderzhanova EA, Tang F, Missig G, Rexrode L, Li K, Pöhlmann ML, Heinz DE, Lardenoije R, Dedic N, McCullough KM, Próchnicki T, Rhomberg T, Martinelli S, Payton A, Robinson AC, Stein V, Latz E, Carlezon WA, Schmidt MV, Murgatroyd C, Berretta S, Klengel T, Pantazopoulos H, Ressler KJ, Gassen NC. Hartmann J, et al. bioRxiv [Preprint]. 2023 Apr 3:2023.04.03.534570. doi: 10.1101/2023.04.03.534570. bioRxiv. 2023. PMID: 37066393 Free PMC article. Updated. Preprint.
The co-chaperone Fkbp5 shapes the acute stress response in the paraventricular nucleus of the hypothalamus of male mice.
Häusl AS, Brix LM, Hartmann J, Pöhlmann ML, Lopez JP, Menegaz D, Brivio E, Engelhardt C, Roeh S, Bajaj T, Rudolph L, Stoffel R, Hafner K, Goss HM, Reul JMHM, Deussing JM, Eder M, Ressler KJ, Gassen NC, Chen A, Schmidt MV. Häusl AS, et al. Among authors: hartmann j. Mol Psychiatry. 2021 Jul;26(7):3060-3076. doi: 10.1038/s41380-021-01044-x. Epub 2021 Mar 1. Mol Psychiatry. 2021. PMID: 33649453 Free PMC article.
Automatically annotated motion tracking identifies a distinct social behavioral profile following chronic social defeat stress.
Bordes J, Miranda L, Reinhardt M, Narayan S, Hartmann J, Newman EL, Brix LM, van Doeselaar L, Engelhardt C, Dillmann L, Mitra S, Ressler KJ, Pütz B, Agakov F, Müller-Myhsok B, Schmidt MV. Bordes J, et al. Among authors: hartmann j. Nat Commun. 2023 Jul 18;14(1):4319. doi: 10.1038/s41467-023-40040-3. Nat Commun. 2023. PMID: 37463994 Free PMC article.
1,276 results