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Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering.
Lee BM, Harold LK, Almeida DV, Afriat-Jurnou L, Aung HL, Forde BM, Hards K, Pidot SJ, Ahmed FH, Mohamed AE, Taylor MC, West NP, Stinear TP, Greening C, Beatson SA, Nuermberger EL, Cook GM, Jackson CJ. Lee BM, et al. Among authors: harold lk. PLoS Pathog. 2020 Feb 7;16(2):e1008287. doi: 10.1371/journal.ppat.1008287. eCollection 2020 Feb. PLoS Pathog. 2020. PMID: 32032366 Free PMC article.
Persistence of the dominant soil phylum Acidobacteria by trace gas scavenging.
Greening C, Carere CR, Rushton-Green R, Harold LK, Hards K, Taylor MC, Morales SE, Stott MB, Cook GM. Greening C, et al. Among authors: harold lk. Proc Natl Acad Sci U S A. 2015 Aug 18;112(33):10497-502. doi: 10.1073/pnas.1508385112. Epub 2015 Aug 3. Proc Natl Acad Sci U S A. 2015. PMID: 26240343 Free PMC article.
Cellular and Structural Basis of Synthesis of the Unique Intermediate Dehydro-F420-0 in Mycobacteria.
Grinter R, Ney B, Brammananth R, Barlow CK, Cordero PRF, Gillett DL, Izoré T, Cryle MJ, Harold LK, Cook GM, Taiaroa G, Williamson DA, Warden AC, Oakeshott JG, Taylor MC, Crellin PK, Jackson CJ, Schittenhelm RB, Coppel RL, Greening C. Grinter R, et al. Among authors: harold lk. mSystems. 2020 May 19;5(3):e00389-20. doi: 10.1128/mSystems.00389-20. mSystems. 2020. PMID: 32430409 Free PMC article.
An amiloride derivative is active against the F1Fo-ATP synthase and cytochrome bd oxidase of Mycobacterium tuberculosis.
Hards K, Cheung CY, Waller N, Adolph C, Keighley L, Tee ZS, Harold LK, Menorca A, Bujaroski RS, Buckley BJ, Tyndall JDA, McNeil MB, Rhee KY, Opel-Reading HK, Krause K, Preiss L, Langer JD, Meier T, Hasenoehrl EJ, Berney M, Kelso MJ, Cook GM. Hards K, et al. Among authors: harold lk. Commun Biol. 2022 Feb 24;5(1):166. doi: 10.1038/s42003-022-03110-8. Commun Biol. 2022. PMID: 35210534 Free PMC article.
14 results