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Modifications of diketopiperazines assembled by cyclodipeptide synthases with cytochrome P450 enzymes.
Appl Microbiol Biotechnol. 2021 Mar;105(6):2277-2285. doi: 10.1007/s00253-021-11178-1. Epub 2021 Feb 24.
Appl Microbiol Biotechnol. 2021.
PMID: 33625545
Free PMC article.
Review.
Elucidation of the Streptoazine Biosynthetic Pathway in Streptomyces aurantiacus Reveals the Presence of a Promiscuous Prenyltransferase/Cyclase.
Liu J, Yang Y, Harken L, Li SM.
Liu J, et al. Among authors: harken l.
J Nat Prod. 2021 Dec 24;84(12):3100-3109. doi: 10.1021/acs.jnatprod.1c00844. Epub 2021 Nov 30.
J Nat Prod. 2021.
PMID: 34846144
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Widely Distributed Bifunctional Bacterial Cytochrome P450 Enzymes Catalyze both Intramolecular C-C Bond Formation in cyclo-l-Tyr-l-Tyr and Its Coupling with Nucleobases.
Liu J, Harken L, Yang Y, Xie X, Li SM.
Liu J, et al. Among authors: harken l.
Angew Chem Int Ed Engl. 2022 May 16;61(21):e202200377. doi: 10.1002/anie.202200377. Epub 2022 Mar 23.
Angew Chem Int Ed Engl. 2022.
PMID: 35201649
Free PMC article.
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Production of Diketopiperazine Derivatives by Pathway Engineering with Different Cyclodipeptide Synthases from Various Streptomyces Strains.
Stierle SA, Harken L, Li SM.
Stierle SA, et al. Among authors: harken l.
ACS Synth Biol. 2023 Jun 16;12(6):1804-1812. doi: 10.1021/acssynbio.3c00115. Epub 2023 May 14.
ACS Synth Biol. 2023.
PMID: 37183364
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P450 in C-C coupling of cyclodipeptides with nucleobases.
Stierle SA, Harken L, Li SM.
Stierle SA, et al. Among authors: harken l.
Methods Enzymol. 2023;693:231-265. doi: 10.1016/bs.mie.2023.09.012. Epub 2023 Oct 12.
Methods Enzymol. 2023.
PMID: 37977732
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Diphtheria-tetanus toxoids-pertussis vaccination does not increase the risk of hospitalization with an infectious illness.
Joffe LS, Glode MP, Gutierrez MK, Wiesenthal A, Luckey DW, Harken L.
Joffe LS, et al. Among authors: harken l.
Pediatr Infect Dis J. 1992 Sep;11(9):730-5. doi: 10.1097/00006454-199209000-00012.
Pediatr Infect Dis J. 1992.
PMID: 1448313
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