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NLGN4X TCR transgenic T cells to treat gliomas.
Krämer C, Kilian M, Chih YC, Kourtesakis A, Hoffmann DC, Boschert T, Koopmann P, Sanghvi K, De Roia A, Jung S, Jähne K, Day B, Shultz LD, Ratliff M, Harbottle R, Green EW, Will R, Wick W, Platten M, Bunse L. Krämer C, et al. Among authors: harbottle r. Neuro Oncol. 2024 Feb 2;26(2):266-278. doi: 10.1093/neuonc/noad172. Neuro Oncol. 2024. PMID: 37715782 Free PMC article.
Prediction of tumor-reactive T cell receptors from scRNA-seq data for personalized T cell therapy.
Tan CL, Lindner K, Boschert T, Meng Z, Rodriguez Ehrenfried A, De Roia A, Haltenhof G, Faenza A, Imperatore F, Bunse L, Lindner JM, Harbottle RP, Ratliff M, Offringa R, Poschke I, Platten M, Green EW. Tan CL, et al. Among authors: harbottle rp. Nat Biotechnol. 2024 Mar 7. doi: 10.1038/s41587-024-02161-y. Online ahead of print. Nat Biotechnol. 2024. PMID: 38454173
Perivascular tenascin C triggers sequential activation of macrophages and endothelial cells to generate a pro-metastatic vascular niche in the lungs.
Hongu T, Pein M, Insua-Rodríguez J, Gutjahr E, Mattavelli G, Meier J, Decker K, Descot A, Bozza M, Harbottle R, Trumpp A, Sinn HP, Riedel A, Oskarsson T. Hongu T, et al. Among authors: harbottle r. Nat Cancer. 2022 Apr;3(4):486-504. doi: 10.1038/s43018-022-00353-6. Epub 2022 Apr 25. Nat Cancer. 2022. PMID: 35469015 Free PMC article.
Delivery of non-viral naked DNA vectors to liver in small weaned pigs by hydrodynamic retrograde intrabiliary injection.
Chan T, Grisch-Chan HM, Schmierer P, Subotic U, Rimann N, Scherer T, Hetzel U, Bozza M, Harbottle R, Williams JA, Steblaj B, Ringer SK, Häberle J, Sidler X, Thöny B. Chan T, et al. Among authors: harbottle r. Mol Ther Methods Clin Dev. 2022 Jan 19;24:268-279. doi: 10.1016/j.omtm.2022.01.006. eCollection 2022 Mar 10. Mol Ther Methods Clin Dev. 2022. PMID: 35211639 Free PMC article.
An episomal DNA vector platform for the persistent genetic modification of pluripotent stem cells and their differentiated progeny.
Roig-Merino A, Urban M, Bozza M, Peterson JD, Bullen L, Büchler-Schäff M, Stäble S, van der Hoeven F, Müller-Decker K, McKay TR, Milsom MD, Harbottle RP. Roig-Merino A, et al. Among authors: harbottle rp. Stem Cell Reports. 2022 Jan 11;17(1):143-158. doi: 10.1016/j.stemcr.2021.11.011. Epub 2021 Dec 22. Stem Cell Reports. 2022. PMID: 34942088 Free PMC article.
Safe and stable generation of induced pluripotent stem cells using doggybone DNA vectors.
Thornton CD, Fielding S, Karbowniczek K, Roig-Merino A, Burrows AE, FitzPatrick LM, Sharaireh A, Tite JP, Mole SE, Harbottle RP, Caproni LJ, McKay TR. Thornton CD, et al. Among authors: harbottle rp. Mol Ther Methods Clin Dev. 2021 Oct 5;23:348-358. doi: 10.1016/j.omtm.2021.09.018. eCollection 2021 Dec 10. Mol Ther Methods Clin Dev. 2021. PMID: 34729381 Free PMC article.
67 results