Hannun YA - Search Results

1

Neutral Sphingomyelinase 2 Inhibition Limits Hepatic Steatosis and Inflammation.

Al-Rashed F, Arefanian H, Madhoun AA, Bahman F, Sindhu S, AlSaeed H, Jacob T, Thomas R, Al-Roub A, Alzaid F, Malik MDZ, Nizam R, Thanaraj TA, Al-Mulla F, Hannun YA, Ahmad R. Al-Rashed F, et al. Among authors: hannun ya. Cells. 2024 Mar 6;13(5):463. doi: 10.3390/cells13050463. Cells. 2024. PMID: 38474427 Free PMC article.

2

Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α.

Al-Rashed F, Ahmad Z, Thomas R, Melhem M, Snider AJ, Obeid LM, Al-Mulla F, Hannun YA, Ahmad R. Al-Rashed F, et al. Among authors: hannun ya. Sci Rep. 2020 Oct 8;10(1):16802. doi: 10.1038/s41598-020-73912-5. Sci Rep. 2020. PMID: 33033337 Free PMC article.

3

The Synergy between Palmitate and TNF-α for CCL2 Production Is Dependent on the TRIF/IRF3 Pathway: Implications for Metabolic Inflammation.

Ahmad R, Al-Roub A, Kochumon S, Akther N, Thomas R, Kumari M, Koshy MS, Tiss A, Hannun YA, Tuomilehto J, Sindhu S, Rosen ED. Ahmad R, et al. Among authors: hannun ya. J Immunol. 2018 May 15;200(10):3599-3611. doi: 10.4049/jimmunol.1701552. Epub 2018 Apr 9. J Immunol. 2018. PMID: 29632147 Free PMC article.

4

Ceramide kinase regulates TNF-α-induced immune responses in human monocytic cells.

Al-Rashed F, Ahmad Z, Snider AJ, Thomas R, Kochumon S, Melhem M, Sindhu S, Obeid LM, Al-Mulla F, Hannun YA, Ahmad R. Al-Rashed F, et al. Among authors: hannun ya. Sci Rep. 2021 Apr 15;11(1):8259. doi: 10.1038/s41598-021-87795-7. Sci Rep. 2021. PMID: 33859296 Free PMC article.

5

Identification of an acid sphingomyelinase ceramide kinase pathway in the regulation of the chemokine CCL5.

Newcomb B, Rhein C, Mileva I, Ahmad R, Clarke CJ, Snider J, Obeid LM, Hannun YA. Newcomb B, et al. Among authors: hannun ya. J Lipid Res. 2018 Jul;59(7):1219-1229. doi: 10.1194/jlr.M084202. Epub 2018 May 3. J Lipid Res. 2018. PMID: 29724781 Free PMC article.

6

A Milk-Fat Based Diet Increases Metastasis in the MMTV-PyMT Mouse Model of Breast Cancer.

Velazquez FN, Viscardi V, Montemage J, Zhang L, Trocchia C, Delamont MM, Ahmad R, Hannun YA, Obeid LM, Snider AJ. Velazquez FN, et al. Among authors: hannun ya. Nutrients. 2021 Jul 15;13(7):2431. doi: 10.3390/nu13072431. Nutrients. 2021. PMID: 34371939 Free PMC article.

7

Sphingolipid metabolism and neutral sphingomyelinases.

Airola MV, Hannun YA. Airola MV, et al. Among authors: hannun ya. Handb Exp Pharmacol. 2013;(215):57-76. doi: 10.1007/978-3-7091-1368-4_3. Handb Exp Pharmacol. 2013. PMID: 23579449 Free PMC article. Review.

8

Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes.

Shamseddine AA, Airola MV, Hannun YA. Shamseddine AA, et al. Among authors: hannun ya. Adv Biol Regul. 2015 Jan;57:24-41. doi: 10.1016/j.jbior.2014.10.002. Epub 2014 Oct 27. Adv Biol Regul. 2015. PMID: 25465297 Free PMC article. Review.

9

P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest.

Shamseddine AA, Clarke CJ, Carroll B, Airola MV, Mohammed S, Rella A, Obeid LM, Hannun YA. Shamseddine AA, et al. Among authors: hannun ya. Cell Death Dis. 2015 Oct 29;6(10):e1947. doi: 10.1038/cddis.2015.268. Cell Death Dis. 2015. PMID: 26512957 Free PMC article.

10

A new twist to the emerging functions of ceramides in cancer: novel role for platelet acid sphingomyelinase in cancer metastasis.

Hannun YA, Newcomb B. Hannun YA, et al. EMBO Mol Med. 2015 Jun;7(6):692-4. doi: 10.15252/emmm.201505161. EMBO Mol Med. 2015. PMID: 25859016 Free PMC article.

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