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Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT.
Bareja A, Lee DE, Ho T, Waitt G, McKay LH, Hannou SA, Orenduff MC, McGreevy KM, Binder A, Ryan CP, Soderblom EJ, Belsky DW, Ferrucci L, Das JK, Banskota N, Kraus VB, Huebner JL, Kraus WE, Huffman KM, Baht GS, Horvath S, Parmer RJ, Miles LA, White JP. Bareja A, et al. Among authors: hannou sa. Cell Rep. 2024 Mar 26;43(3):113881. doi: 10.1016/j.celrep.2024.113881. Epub 2024 Mar 4. Cell Rep. 2024. PMID: 38442019 Free PMC article.
β-Cell-Specific E2f1 Deficiency Impairs Glucose Homeostasis, β-Cell Identity, and Insulin Secretion.
Oger F, Bourouh C, Friano ME, Courty E, Rolland L, Gromada X, Moreno M, Carney C, Rabhi N, Durand E, Amanzougarene S, Berberian L, Derhourhi M, Blanc E, Hannou SA, Denechaud PD, Benfodda Z, Meffre P, Fajas L, Kerr-Conte J, Pattou F, Froguel P, Pourcet B, Bonnefond A, Collombat P, Annicotte JS. Oger F, et al. Among authors: hannou sa. Diabetes. 2023 Aug 1;72(8):1112-1126. doi: 10.2337/db22-0604. Diabetes. 2023. PMID: 37216637
"Metformin Impairs Intestinal Fructose Metabolism".
Tong W, Hannou SA, Sargsyan A, Zhang GF, Grimsrud PA, Astapova I, Herman MA. Tong W, et al. Among authors: hannou sa. bioRxiv [Preprint]. 2023 May 15:2023.04.17.537251. doi: 10.1101/2023.04.17.537251. bioRxiv. 2023. PMID: 37131695 Free PMC article. Preprint.
HGFAC is a ChREBP-regulated hepatokine that enhances glucose and lipid homeostasis.
Sargsyan A, Doridot L, Hannou SA, Tong W, Srinivasan H, Ivison R, Monn R, Kou HH, Haldeman JM, Arlotto M, White PJ, Grimsrud PA, Astapova I, Tsai LT, Herman MA. Sargsyan A, et al. Among authors: hannou sa. JCI Insight. 2023 Jan 10;8(1):e153740. doi: 10.1172/jci.insight.153740. JCI Insight. 2023. PMID: 36413406 Free PMC article.
The intestine is a major contributor to circulating succinate in mice.
Tong W, Hannou SA, Wang Y, Astapova I, Sargsyan A, Monn R, Thiriveedi V, Li D, McCann JR, Rawls JF, Roper J, Zhang GF, Herman MA. Tong W, et al. Among authors: hannou sa. FASEB J. 2022 Oct;36(10):e22546. doi: 10.1096/fj.202200135RR. FASEB J. 2022. PMID: 36106538 Free PMC article.
CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway.
Deleye Y, Cotte AK, Hannou SA, Hennuyer N, Bernard L, Derudas B, Caron S, Legry V, Vallez E, Dorchies E, Martin N, Lancel S, Annicotte JS, Bantubungi K, Pourtier A, Raverdy V, Pattou F, Lefebvre P, Abbadie C, Staels B, Haas JT, Paumelle R. Deleye Y, et al. Among authors: hannou sa. J Biol Chem. 2020 Dec 11;295(50):17310-17322. doi: 10.1074/jbc.RA120.012543. Epub 2020 Oct 9. J Biol Chem. 2020. PMID: 33037071 Free PMC article.
Hepatic PPARα is critical in the metabolic adaptation to sepsis.
Paumelle R, Haas JT, Hennuyer N, Baugé E, Deleye Y, Mesotten D, Langouche L, Vanhoutte J, Cudejko C, Wouters K, Hannou SA, Legry V, Lancel S, Lalloyer F, Polizzi A, Smati S, Gourdy P, Vallez E, Bouchaert E, Derudas B, Dehondt H, Gheeraert C, Fleury S, Tailleux A, Montagner A, Wahli W, Van Den Berghe G, Guillou H, Dombrowicz D, Staels B. Paumelle R, et al. Among authors: hannou sa. J Hepatol. 2019 May;70(5):963-973. doi: 10.1016/j.jhep.2018.12.037. Epub 2019 Jan 21. J Hepatol. 2019. PMID: 30677458 Free PMC article.
22 results