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A Phase I Expansion Cohort Study Evaluating the Safety and Efficacy of the CHK1 Inhibitor LY2880070 with Low-dose Gemcitabine in Patients with Metastatic Pancreatic Adenocarcinoma.
Huffman BM, Feng H, Parmar K, Wang J, Kapner KS, Kochupurakkal B, Martignetti DB, Sadatrezaei G, Abrams TA, Biller LH, Giannakis M, Ng K, Patel AK, Perez KJ, Singh H, Rubinson DA, Schlechter BL, Andrews E, Hannigan AM, Dunwell S, Getchell Z, Raghavan S, Wolpin BM, Fortier C, D'Andrea AD, Aguirre AJ, Shapiro GI, Cleary JM. Huffman BM, et al. Among authors: hannigan am. Clin Cancer Res. 2023 Dec 15;29(24):5047-5056. doi: 10.1158/1078-0432.CCR-23-2005. Clin Cancer Res. 2023. PMID: 37819936
RAS/RAF Comutation and ERBB2 Copy Number Modulates HER2 Heterogeneity and Responsiveness to HER2-directed Therapy in Colorectal Cancer.
Singh H, Sahgal P, Kapner K, Corsello SM, Gupta H, Gujrathi R, Li YY, Cherniack AD, El Alam R, Kerfoot J, Andrews E, Lee A, Nambiar C, Hannigan AM, Remland J, Brais L, Leahy ME, Rubinson DA, Schlechter BL, Meyerson M, Kuang Y, Paweletz CP, Lee JK, Quintanilha JCF, Aguirre AJ, Perez KJ, Huffman BM, Rossi H, Abrams TA, Kabraji S, Trusolino L, Bertotti A, Sicinska ET, Parikh AR, Wolpin BM, Schrock AB, Giannakis M, Ng K, Meyerhardt JA, Hornick JL, Sethi NS, Cleary JM. Singh H, et al. Among authors: hannigan am. Clin Cancer Res. 2024 Apr 15;30(8):1669-1684. doi: 10.1158/1078-0432.CCR-23-2581. Clin Cancer Res. 2024. PMID: 38345769
A new quinoline-based chemical probe inhibits the autophagy-related cysteine protease ATG4B.
Bosc D, Vezenkov L, Bortnik S, An J, Xu J, Choutka C, Hannigan AM, Kovacic S, Loo S, Clark PGK, Chen G, Guay-Ross RN, Yang K, Dragowska WH, Zhang F, Go NE, Leung A, Honson NS, Pfeifer TA, Gleave M, Bally M, Jones SJ, Gorski SM, Young RN. Bosc D, et al. Among authors: hannigan am. Sci Rep. 2018 Aug 3;8(1):11653. doi: 10.1038/s41598-018-29900-x. Sci Rep. 2018. PMID: 30076329 Free PMC article.
Does load uncertainty affect adaptation to catch training?
Berg WP, Richards BJ, Hannigan AM, Biller KL, Hughes MR. Berg WP, et al. Among authors: hannigan am. Exp Brain Res. 2016 Sep;234(9):2595-607. doi: 10.1007/s00221-016-4664-y. Epub 2016 May 23. Exp Brain Res. 2016. PMID: 27215774
An executioner caspase regulates autophagy.
Hou YC, Hannigan AM, Gorski SM. Hou YC, et al. Among authors: hannigan am. Autophagy. 2009 May;5(4):530-3. doi: 10.4161/auto.5.4.8061. Epub 2009 May 2. Autophagy. 2009. PMID: 19242106 Free PMC article.
Macroautophagy: the key ingredient to a healthy diet?
Hannigan AM, Gorski SM. Hannigan AM, et al. Autophagy. 2009 Feb;5(2):140-51. doi: 10.4161/auto.5.2.7529. Epub 2009 Feb 3. Autophagy. 2009. PMID: 19098459 Free PMC article. Review.