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Obeticholic Acid Modulates Serum Metabolites and Gene Signatures Characteristic of Human NASH and Attenuates Inflammation and Fibrosis Progression in Ldlr-/-.Leiden Mice.
Morrison MC, Verschuren L, Salic K, Verheij J, Menke A, Wielinga PY, Iruarrizaga-Lejarreta M, Gole L, Yu WM, Turner S, Caspers MPM, Martínez-Arranz I, Pieterman E, Stoop R, van Koppen A, van den Hoek AM, Mato JM, Hanemaaijer R, Alonso C, Kleemann R. Morrison MC, et al. Among authors: hanemaaijer r. Hepatol Commun. 2018 Oct 29;2(12):1513-1532. doi: 10.1002/hep4.1270. eCollection 2018 Dec. Hepatol Commun. 2018. PMID: 30556039 Free PMC article.
Butyrate Protects against Diet-Induced NASH and Liver Fibrosis and Suppresses Specific Non-Canonical TGF-β Signaling Pathways in Human Hepatic Stellate Cells.
Gart E, van Duyvenvoorde W, Toet K, Caspers MPM, Verschuren L, Nielsen MJ, Leeming DJ, Souto Lima E, Menke A, Hanemaaijer R, Keijer J, Salic K, Kleemann R, Morrison MC. Gart E, et al. Among authors: hanemaaijer r. Biomedicines. 2021 Dec 20;9(12):1954. doi: 10.3390/biomedicines9121954. Biomedicines. 2021. PMID: 34944770 Free PMC article.
Uncovering a Predictive Molecular Signature for the Onset of NASH-Related Fibrosis in a Translational NASH Mouse Model.
van Koppen A, Verschuren L, van den Hoek AM, Verheij J, Morrison MC, Li K, Nagabukuro H, Costessi A, Caspers MPM, van den Broek TJ, Sagartz J, Kluft C, Beysen C, Emson C, van Gool AJ, Goldschmeding R, Stoop R, Bobeldijk-Pastorova I, Turner SM, Hanauer G, Hanemaaijer R. van Koppen A, et al. Among authors: hanemaaijer r. Cell Mol Gastroenterol Hepatol. 2017 Oct 14;5(1):83-98.e10. doi: 10.1016/j.jcmgh.2017.10.001. eCollection 2018. Cell Mol Gastroenterol Hepatol. 2017. PMID: 29276754 Free PMC article.
Elevated expression levels of lysyl oxidases protect against aortic aneurysm progression in Marfan syndrome.
Busnadiego O, Gorbenko Del Blanco D, González-Santamaría J, Habashi JP, Calderon JF, Sandoval P, Bedja D, Guinea-Viniegra J, Lopez-Cabrera M, Rosell-Garcia T, Snabel JM, Hanemaaijer R, Forteza A, Dietz HC, Egea G, Rodriguez-Pascual F. Busnadiego O, et al. Among authors: hanemaaijer r. J Mol Cell Cardiol. 2015 Aug;85:48-57. doi: 10.1016/j.yjmcc.2015.05.008. Epub 2015 May 16. J Mol Cell Cardiol. 2015. PMID: 25988230 Free article.
Role of caveolin-1 in fibrotic diseases.
Gvaramia D, Blaauboer ME, Hanemaaijer R, Everts V. Gvaramia D, et al. Among authors: hanemaaijer r. Matrix Biol. 2013 Aug 8;32(6):307-15. doi: 10.1016/j.matbio.2013.03.005. Epub 2013 Apr 11. Matrix Biol. 2013. PMID: 23583521 Free article. Review.
A clinical evaluation of statin pleiotropy: statins selectively and dose-dependently reduce vascular inflammation.
van der Meij E, Koning GG, Vriens PW, Peeters MF, Meijer CA, Kortekaas KE, Dalman RL, van Bockel JH, Hanemaaijer R, Kooistra T, Kleemann R, Lindeman JH. van der Meij E, et al. Among authors: hanemaaijer r. PLoS One. 2013;8(1):e53882. doi: 10.1371/journal.pone.0053882. Epub 2013 Jan 22. PLoS One. 2013. PMID: 23349755 Free PMC article. Clinical Trial.
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