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Active eosinophils regulate host defence and immune responses in colitis.
Gurtner A, Borrelli C, Gonzalez-Perez I, Bach K, Acar IE, Núñez NG, Crepaz D, Handler K, Vu VP, Lafzi A, Stirm K, Raju D, Gschwend J, Basler K, Schneider C, Slack E, Valenta T, Becher B, Krebs P, Moor AE, Arnold IC. Gurtner A, et al. Among authors: handler k. Nature. 2023 Mar;615(7950):151-157. doi: 10.1038/s41586-022-05628-7. Epub 2022 Dec 12. Nature. 2023. PMID: 36509106 Free PMC article.
TiO2 nanoparticles abrogate the protective effect of the Crohn's disease-associated variation within the PTPN22 gene locus.
Schwarzfischer M, Niechcial A, Handler K, Morsy Y, Wawrzyniak M, Laimbacher AS, Atrott K, Manzini R, Baebler K, Hering L, Katkeviciutė E, Häfliger J, Lang S, Keller ME, Woodtli J, Eisenbeiss L, Kraemer T, Schraner EM, Wiesendanger M, Zeissig S, Rogler G, Moor AE, Scharl M, Spalinger MR. Schwarzfischer M, et al. Among authors: handler k. Gut. 2023 Jun;72(6):1101-1114. doi: 10.1136/gutjnl-2021-325911. Epub 2022 Oct 3. Gut. 2023. PMID: 36191962
Identifying Spatial Co-occurrence in Healthy and InflAmed tissues (ISCHIA).
Lafzi A, Borrelli C, Baghai Sain S, Bach K, Kretz JA, Handler K, Regan-Komito D, Ficht X, Frei A, Moor A. Lafzi A, et al. Among authors: handler k. Mol Syst Biol. 2024 Feb;20(2):98-119. doi: 10.1038/s44320-023-00006-5. Epub 2024 Jan 15. Mol Syst Biol. 2024. PMID: 38225383 Free PMC article.
A GGC-repeat expansion in ZFHX3 encoding polyglycine causes spinocerebellar ataxia type 4 and impairs autophagy.
Figueroa KP, Gross C, Buena-Atienza E, Paul S, Gandelman M, Kakar N, Sturm M, Casadei N, Admard J, Park J, Zühlke C, Hellenbroich Y, Pozojevic J, Balachandran S, Händler K, Zittel S, Timmann D, Erdlenbruch F, Herrmann L, Feindt T, Zenker M, Klopstock T, Dufke C, Scoles DR, Koeppen A, Spielmann M, Riess O, Ossowski S, Haack TB, Pulst SM. Figueroa KP, et al. Among authors: handler k. Nat Genet. 2024 Apr 29. doi: 10.1038/s41588-024-01719-5. Online ahead of print. Nat Genet. 2024. PMID: 38684900
Identification of drug candidates targeting monocyte reprogramming in people living with HIV.
Knoll R, Bonaguro L, Dos Santos JC, Warnat-Herresthal S, Jacobs-Cleophas MCP, Blümel E, Reusch N, Horne A, Herbert M, Nuesch-Germano M, Otten T, van der Heijden WA, van de Wijer L, Shalek AK, Händler K, Becker M, Beyer MD, Netea MG, Joosten LAB, van der Ven AJAM, Schultze JL, Aschenbrenner AC. Knoll R, et al. Among authors: handler k. Front Immunol. 2023 Nov 20;14:1275136. doi: 10.3389/fimmu.2023.1275136. eCollection 2023. Front Immunol. 2023. PMID: 38077315 Free PMC article.
Systemic alterations in neutrophils and their precursors in early-stage chronic obstructive pulmonary disease.
Kapellos TS, Baßler K, Fujii W, Nalkurthi C, Schaar AC, Bonaguro L, Pecht T, Galvao I, Agrawal S, Saglam A, Dudkin E, Frishberg A, de Domenico E, Horne A, Donovan C, Kim RY, Gallego-Ortega D, Gillett TE, Ansari M, Schulte-Schrepping J, Offermann N, Antignano I, Sivri B, Lu W, Eapen MS, van Uelft M, Osei-Sarpong C, van den Berge M, Donker HC, Groen HJM, Sohal SS, Klein J, Schreiber T, Feißt A, Yildirim AÖ, Schiller HB, Nawijn MC, Becker M, Händler K, Beyer M, Capasso M, Ulas T, Hasenauer J, Pizarro C, Theis FJ, Hansbro PM, Skowasch D, Schultze JL. Kapellos TS, et al. Among authors: handler k. Cell Rep. 2023 Jun 27;42(6):112525. doi: 10.1016/j.celrep.2023.112525. Epub 2023 May 26. Cell Rep. 2023. PMID: 37243592 Free PMC article.
59 results