HMGB2 is a negative regulator of telomerase activity in human embryonic stem and progenitor cells.
Kučírek M, Bagherpoor AJ, Jaroš J, Hampl A, Štros M.
Kučírek M, et al. Among authors: hampl a.
FASEB J. 2019 Dec 1;33(12):14307-14324. doi: 10.1096/fj.201901465RRR. Epub 2019 Oct 26.
FASEB J. 2019.
PMID: 31661640
Our findings on differential roles of HMGB1 and HMGB2 proteins in regulation of telomerase activity may suggest another possible outcome of HMGB1 targeting in cells, which is currently a promising approach aiming at increasing the anticancer activity of cytotoxic agents.-K …
Our findings on differential roles of HMGB1 and HMGB2 proteins in regulation of telomerase activity may suggest another possible outcome of …