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Alternative approaches for identifying acute systemic toxicity: Moving from research to regulatory testing.
Hamm J, Sullivan K, Clippinger AJ, Strickland J, Bell S, Bhhatarai B, Blaauboer B, Casey W, Dorman D, Forsby A, Garcia-Reyero N, Gehen S, Graepel R, Hotchkiss J, Lowit A, Matheson J, Reaves E, Scarano L, Sprankle C, Tunkel J, Wilson D, Xia M, Zhu H, Allen D. Hamm J, et al. Toxicol In Vitro. 2017 Jun;41:245-259. doi: 10.1016/j.tiv.2017.01.004. Epub 2017 Jan 6. Toxicol In Vitro. 2017. PMID: 28069485 Free PMC article. Review.
A Curated Database of Rodent Uterotrophic Bioactivity.
Kleinstreuer NC, Ceger PC, Allen DG, Strickland J, Chang X, Hamm JT, Casey WM. Kleinstreuer NC, et al. Among authors: hamm jt. Environ Health Perspect. 2016 May;124(5):556-62. doi: 10.1289/ehp.1510183. Epub 2015 Oct 2. Environ Health Perspect. 2016. PMID: 26431337 Free PMC article. Review.
CONCLUSIONS: This uterotrophic database provides a valuable resource for understanding in vivo outcome variability and for evaluating the performance of in vitro assays that measure estrogenic activity. CITATION: Kleinstreuer NC, Ceger PC, Allen DG, Strickland J, Chang X, …
CONCLUSIONS: This uterotrophic database provides a valuable resource for understanding in vivo outcome variability and for evaluating the pe …
Current ecotoxicity testing needs among selected U.S. federal agencies.
Ceger P, Garcia-Reyero Vinas N, Allen D, Arnold E, Bloom R, Brennan JC, Clarke C, Eisenreich K, Fay K, Hamm J, Henry PFP, Horak K, Hunter W, Judkins D, Klein P, Kleinstreuer N, Koehrn K, LaLone CA, Laurenson JP, Leet JK, Lowit A, Lynn SG, Norberg-King T, Perkins EJ, Petersen EJ, Rattner BA, Sprankle CS, Steeger T, Warren JE, Winfield S, Odenkirchen E. Ceger P, et al. Among authors: hamm j. Regul Toxicol Pharmacol. 2022 Aug;133:105195. doi: 10.1016/j.yrtph.2022.105195. Epub 2022 Jun 2. Regul Toxicol Pharmacol. 2022. PMID: 35660046 Free PMC article. Review.
Advancing toxicology research using in vivo high throughput toxicology with small fish models.
Planchart A, Mattingly CJ, Allen D, Ceger P, Casey W, Hinton D, Kanungo J, Kullman SW, Tal T, Bondesson M, Burgess SM, Sullivan C, Kim C, Behl M, Padilla S, Reif DM, Tanguay RL, Hamm J. Planchart A, et al. Among authors: hamm j. ALTEX. 2016;33(4):435-452. doi: 10.14573/altex.1601281. Epub 2016 Jun 21. ALTEX. 2016. PMID: 27328013 Free PMC article.
Characterizing sources of variability in zebrafish embryo screening protocols.
Hamm JT, Ceger P, Allen D, Stout M, Maull EA, Baker G, Zmarowski A, Padilla S, Perkins E, Planchart A, Stedman D, Tal T, Tanguay RL, Volz DC, Wilbanks MS, Walker NJ. Hamm JT, et al. ALTEX. 2019;36(1):103-120. doi: 10.14573/altex.1804162. Epub 2018 Nov 10. ALTEX. 2019. PMID: 30415271 Free PMC article.
Differential modulation of FXR activity by chlorophacinone and ivermectin analogs.
Hsu CW, Hsieh JH, Huang R, Pijnenburg D, Khuc T, Hamm J, Zhao J, Lynch C, van Beuningen R, Chang X, Houtman R, Xia M. Hsu CW, et al. Among authors: hamm j. Toxicol Appl Pharmacol. 2016 Dec 15;313:138-148. doi: 10.1016/j.taap.2016.10.017. Epub 2016 Oct 20. Toxicol Appl Pharmacol. 2016. PMID: 27773686 Free PMC article.
Implementation of Zebrafish Ontologies for Toxicology Screening.
Thessen AE, Marvel S, Achenbach JC, Fischer S, Haendel MA, Hayward K, Klüver N, Könemann S, Legradi J, Lein P, Leong C, Mylroie JE, Padilla S, Perone D, Planchart A, Prieto RM, Muriana A, Quevedo C, Reif D, Ryan K, Stinckens E, Truong L, Vergauwen L, Vom Berg C, Wilbanks M, Yaghoobi B, Hamm J. Thessen AE, et al. Among authors: hamm j. Front Toxicol. 2022 Mar 11;4:817999. doi: 10.3389/ftox.2022.817999. eCollection 2022. Front Toxicol. 2022. PMID: 35387429 Free PMC article.
606 results