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β-Hydroxybutyrate suppresses colorectal cancer.
Dmitrieva-Posocco O, Wong AC, Lundgren P, Golos AM, Descamps HC, Dohnalová L, Cramer Z, Tian Y, Yueh B, Eskiocak O, Egervari G, Lan Y, Liu J, Fan J, Kim J, Madhu B, Schneider KM, Khoziainova S, Andreeva N, Wang Q, Li N, Furth EE, Bailis W, Kelsen JR, Hamilton KE, Kaestner KH, Berger SL, Epstein JA, Jain R, Li M, Beyaz S, Lengner CJ, Katona BW, Grivennikov SI, Thaiss CA, Levy M. Dmitrieva-Posocco O, et al. Among authors: hamilton ke. Nature. 2022 May;605(7908):160-165. doi: 10.1038/s41586-022-04649-6. Epub 2022 Apr 27. Nature. 2022. PMID: 35477756 Free PMC article.
Long-lived keratin 15+ esophageal progenitor cells contribute to homeostasis and regeneration.
Giroux V, Lento AA, Islam M, Pitarresi JR, Kharbanda A, Hamilton KE, Whelan KA, Long A, Rhoades B, Tang Q, Nakagawa H, Lengner CJ, Bass AJ, Wileyto EP, Klein-Szanto AJ, Wang TC, Rustgi AK. Giroux V, et al. Among authors: hamilton ke. J Clin Invest. 2017 Jun 1;127(6):2378-2391. doi: 10.1172/JCI88941. Epub 2017 May 8. J Clin Invest. 2017. PMID: 28481227 Free PMC article.
Mouse Intestinal Krt15+ Crypt Cells Are Radio-Resistant and Tumor Initiating.
Giroux V, Stephan J, Chatterji P, Rhoades B, Wileyto EP, Klein-Szanto AJ, Lengner CJ, Hamilton KE, Rustgi AK. Giroux V, et al. Among authors: hamilton ke. Stem Cell Reports. 2018 Jun 5;10(6):1947-1958. doi: 10.1016/j.stemcr.2018.04.022. Epub 2018 May 24. Stem Cell Reports. 2018. PMID: 29805107 Free PMC article.
The LIN28B-IMP1 post-transcriptional regulon has opposing effects on oncogenic signaling in the intestine.
Chatterji P, Hamilton KE, Liang S, Andres SF, Wijeratne HRS, Mizuno R, Simon LA, Hicks PD, Foley SW, Pitarresi JR, Klein-Szanto AJ, Mah AT, Van Landeghem L, Gregory BD, Lengner CJ, Madison BB, Shah P, Rustgi AK. Chatterji P, et al. Among authors: hamilton ke. Genes Dev. 2018 Aug 1;32(15-16):1020-1034. doi: 10.1101/gad.314369.118. Genes Dev. 2018. PMID: 30068703 Free PMC article.
IMP1 3' UTR shortening enhances metastatic burden in colorectal cancer.
Andres SF, Williams KN, Plesset JB, Headd JJ, Mizuno R, Chatterji P, Lento AA, Klein-Szanto AJ, Mick R, Hamilton KE, Rustgi AK. Andres SF, et al. Among authors: hamilton ke. Carcinogenesis. 2019 Jun 10;40(4):569-579. doi: 10.1093/carcin/bgy153. Carcinogenesis. 2019. PMID: 30407516 Free PMC article.
Single cell transcriptomic analysis reveals cellular diversity of murine esophageal epithelium.
Kabir MF, Karami AL, Cruz-Acuña R, Klochkova A, Saxena R, Mu A, Murray MG, Cruz J, Fuller AD, Clevenger MH, Chitrala KN, Tan Y, Keith K, Madzo J, Huang H, Jelinek J, Karakasheva T, Hamilton KE, Muir AB, Tétreault MP, Whelan KA. Kabir MF, et al. Among authors: hamilton ke. Nat Commun. 2022 Apr 20;13(1):2167. doi: 10.1038/s41467-022-29747-x. Nat Commun. 2022. PMID: 35443762 Free PMC article.
Autophagic state prospectively identifies facultative stem cells in the intestinal epithelium.
Johnson NM, Parham LR, Na J, Monaghan KE, Kolev HM, Klochkova A, Kim MS, Danan CH, Cramer Z, Simon LA, Naughton KE, Adams-Tzivelekidis S, Tian Y, Williams PA, Leu NA, Sidoli S, Whelan KA, Li N, Lengner CJ, Hamilton KE. Johnson NM, et al. Among authors: hamilton ke. EMBO Rep. 2022 Nov 7;23(11):e55209. doi: 10.15252/embr.202255209. Epub 2022 Sep 19. EMBO Rep. 2022. PMID: 36120829 Free PMC article.
Geometric engineering of organoid culture for enhanced organogenesis in a dish.
Park SE, Kang S, Paek J, Georgescu A, Chang J, Yi AY, Wilkins BJ, Karakasheva TA, Hamilton KE, Huh DD. Park SE, et al. Among authors: hamilton ke. Nat Methods. 2022 Nov;19(11):1449-1460. doi: 10.1038/s41592-022-01643-8. Epub 2022 Oct 24. Nat Methods. 2022. PMID: 36280722 Free PMC article.
75 results