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Antifungal potential of marine natural products.
El-Hossary EM, Cheng C, Hamed MM, El-Sayed Hamed AN, Ohlsen K, Hentschel U, Abdelmohsen UR. El-Hossary EM, et al. Among authors: hamed mm. Eur J Med Chem. 2017 Jan 27;126:631-651. doi: 10.1016/j.ejmech.2016.11.022. Epub 2016 Nov 14. Eur J Med Chem. 2017. PMID: 27936443 Review.
Development of potential preclinical candidates with promising in vitro ADME profile for the inhibition of type 1 and type 2 17β-Hydroxysteroid dehydrogenases: Design, synthesis, and biological evaluation.
Abdelsamie AS, Salah M, Siebenbürger L, Hamed MM, Börger C, van Koppen CJ, Frotscher M, Hartmann RW. Abdelsamie AS, et al. Among authors: hamed mm. Eur J Med Chem. 2019 Sep 15;178:93-107. doi: 10.1016/j.ejmech.2019.05.084. Epub 2019 May 31. Eur J Med Chem. 2019. PMID: 31176098
A New PqsR Inverse Agonist Potentiates Tobramycin Efficacy to Eradicate Pseudomonas aeruginosa Biofilms.
Schütz C, Ho DK, Hamed MM, Abdelsamie AS, Röhrig T, Herr C, Kany AM, Rox K, Schmelz S, Siebenbürger L, Wirth M, Börger C, Yahiaoui S, Bals R, Scrima A, Blankenfeldt W, Horstmann JC, Christmann R, Murgia X, Koch M, Berwanger A, Loretz B, Hirsch AKH, Hartmann RW, Lehr CM, Empting M. Schütz C, et al. Among authors: hamed mm. Adv Sci (Weinh). 2021 Jun;8(12):e2004369. doi: 10.1002/advs.202004369. Epub 2021 Mar 18. Adv Sci (Weinh). 2021. PMID: 34165899 Free PMC article.
Redesigning of the cap conformation and symmetry of the diphenylethyne core to yield highly potent pan-genotypic NS5A inhibitors with high potency and high resistance barrier.
Abdallah M, Hamed MM, Frakolaki E, Katsamakas S, Vassilaki N, Bartenschlager R, Zoidis G, Hirsch AKH, Abdel-Halim M, Abadi AH. Abdallah M, et al. Among authors: hamed mm. Eur J Med Chem. 2022 Feb 5;229:114034. doi: 10.1016/j.ejmech.2021.114034. Epub 2021 Dec 7. Eur J Med Chem. 2022. PMID: 34959173
844 results