Hambright WS - Search Results

1

The Senolytic Drug Fisetin Attenuates Bone Degeneration in the Zmpste24 ^-/- Progeria Mouse Model.

Hambright WS, Mu X, Gao X, Guo P, Kawakami Y, Mitchell J, Mullen M, Nelson AL, Bahney C, Nishimura H, Hellwinkel J, Eck A, Huard J. Hambright WS, et al. J Osteoporos. 2023 Feb 22;2023:5572754. doi: 10.1155/2023/5572754. eCollection 2023. J Osteoporos. 2023. PMID: 36875869 Free PMC article.

2

Murine models of accelerated aging and musculoskeletal disease.

Hambright WS, Niedernhofer LJ, Huard J, Robbins PD. Hambright WS, et al. Bone. 2019 Aug;125:122-127. doi: 10.1016/j.bone.2019.03.002. Epub 2019 Mar 4. Bone. 2019. PMID: 30844492 Review.

3

Rapamycin Rescues Age-Related Changes in Muscle-Derived Stem/Progenitor Cells from Progeroid Mice.

Kawakami Y, Hambright WS, Takayama K, Mu X, Lu A, Cummins JH, Matsumoto T, Yurube T, Kuroda R, Kurosaka M, Fu FH, Robbins PD, Niedernhofer LJ, Huard J. Kawakami Y, et al. Among authors: hambright ws. Mol Ther Methods Clin Dev. 2019 May 30;14:64-76. doi: 10.1016/j.omtm.2019.05.011. eCollection 2019 Sep 13. Mol Ther Methods Clin Dev. 2019. PMID: 31312666 Free PMC article.

4

Cytoskeleton stiffness regulates cellular senescence and innate immune response in Hutchinson-Gilford Progeria Syndrome.

Mu X, Tseng C, Hambright WS, Matre P, Lin CY, Chanda P, Chen W, Gu J, Ravuri S, Cui Y, Zhong L, Cooke JP, Niedernhofer LJ, Robbins PD, Huard J. Mu X, et al. Among authors: hambright ws. Aging Cell. 2020 Aug;19(8):e13152. doi: 10.1111/acel.13152. Epub 2020 Jul 25. Aging Cell. 2020. PMID: 32710480 Free PMC article.

5

Rapamycin for aging stem cells.

Hambright WS, Philippon MJ, Huard J. Hambright WS, et al. Aging (Albany NY). 2020 Aug 4;12(15):15184-15185. doi: 10.18632/aging.103816. Epub 2020 Aug 4. Aging (Albany NY). 2020. PMID: 32756013 Free PMC article. No abstract available.

6

Aberrant RhoA activation in macrophages increases senescence-associated secretory phenotypes and ectopic calcification in muscular dystrophic mice.

Mu X, Lin CY, Hambright WS, Tang Y, Ravuri S, Lu A, Matre P, Chen W, Gao X, Cui Y, Zhong L, Wang B, Huard J. Mu X, et al. Among authors: hambright ws. Aging (Albany NY). 2020 Dec 23;12(24):24853-24871. doi: 10.18632/aging.202413. Epub 2020 Dec 23. Aging (Albany NY). 2020. PMID: 33361519 Free PMC article.

7

Senolytic elimination of senescent macrophages restores muscle stem cell function in severely dystrophic muscle.

Liu L, Yue X, Sun Z, Hambright WS, Feng Q, Cui Y, Huard J, Robbins PD, Wang Z, Mu X. Liu L, et al. Among authors: hambright ws. Aging (Albany NY). 2022 Sep 8;14(19):7650-7661. doi: 10.18632/aging.204275. Epub 2022 Sep 8. Aging (Albany NY). 2022. PMID: 36084954 Free PMC article.

8

Reduction of senescent fibro-adipogenic progenitors in progeria-aged muscle by senolytics rescues the function of muscle stem cells.

Liu L, Yue X, Sun Z, Hambright WS, Wei J, Li Y, Matre P, Cui Y, Wang Z, Rodney G, Huard J, Robbins PD, Mu X. Liu L, et al. Among authors: hambright ws. J Cachexia Sarcopenia Muscle. 2022 Dec;13(6):3137-3148. doi: 10.1002/jcsm.13101. Epub 2022 Oct 11. J Cachexia Sarcopenia Muscle. 2022. PMID: 36218080 Free PMC article.

9

Mechanical strain drives exosome production, function, and miRNA cargo in C2C12 muscle progenitor cells.

Mullen M, Williams K, LaRocca T, Duke V, Hambright WS, Ravuri SK, Bahney CS, Ehrhart N, Huard J. Mullen M, et al. Among authors: hambright ws. J Orthop Res. 2023 Jun;41(6):1186-1197. doi: 10.1002/jor.25467. Epub 2022 Oct 29. J Orthop Res. 2023. PMID: 36250617

10

Cellular expansion of MSCs: Shifting the regenerative potential.

Miclau K, Hambright WS, Huard J, Stoddart MJ, Bahney CS. Miclau K, et al. Among authors: hambright ws. Aging Cell. 2023 Jan;22(1):e13759. doi: 10.1111/acel.13759. Epub 2022 Dec 19. Aging Cell. 2023. PMID: 36536521 Free PMC article. Review.

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