Hall J - Search Results

1

Pharmacological inhibition of Lin28 promotes ketogenesis and restores lipid homeostasis in models of non-alcoholic fatty liver disease.

Lekka E, Kokanovic A, Mosole S, Civenni G, Schmidli S, Laski A, Ghidini A, Iyer P, Berk C, Behera A, Catapano CV, Hall J. Lekka E, et al. Among authors: hall j. Nat Commun. 2022 Dec 26;13(1):7940. doi: 10.1038/s41467-022-35481-1. Nat Commun. 2022. PMID: 36572670 Free PMC article.

2

Short loop-targeting oligoribonucleotides antagonize Lin28 and enable pre-let-7 processing and suppression of cell growth in let-7-deficient cancer cells.

Roos M, Rebhan MA, Lucic M, Pavlicek D, Pradere U, Towbin H, Civenni G, Catapano CV, Hall J. Roos M, et al. Among authors: hall j. Nucleic Acids Res. 2015 Jan;43(2):e9. doi: 10.1093/nar/gku1090. Epub 2014 Nov 6. Nucleic Acids Res. 2015. PMID: 25378324 Free PMC article.

3

Site-specific conjugation of drug-like fragments to an antimiR scaffold as a strategy to target miRNAs inside RISC.

Brunschweiger A, Gebert LF, Lucic M, Pradère U, Jahns H, Berk C, Hunziker J, Hall J. Brunschweiger A, et al. Among authors: hall j. Chem Commun (Camb). 2016 Jan 4;52(1):156-9. doi: 10.1039/c5cc07478a. Chem Commun (Camb). 2016. PMID: 26505838

4

Activation of the Lin28/let-7 Axis by Loss of ESE3/EHF Promotes a Tumorigenic and Stem-like Phenotype in Prostate Cancer.

Albino D, Civenni G, Dallavalle C, Roos M, Jahns H, Curti L, Rossi S, Pinton S, D'Ambrosio G, Sessa F, Hall J, Catapano CV, Carbone GM. Albino D, et al. Among authors: hall j. Cancer Res. 2016 Jun 15;76(12):3629-43. doi: 10.1158/0008-5472.CAN-15-2665. Epub 2016 May 2. Cancer Res. 2016. PMID: 27197175

5

A Small-Molecule Inhibitor of Lin28.

Roos M, Pradère U, Ngondo RP, Behera A, Allegrini S, Civenni G, Zagalak JA, Marchand JR, Menzi M, Towbin H, Scheuermann J, Neri D, Caflisch A, Catapano CV, Ciaudo C, Hall J. Roos M, et al. Among authors: hall j. ACS Chem Biol. 2016 Oct 21;11(10):2773-2781. doi: 10.1021/acschembio.6b00232. Epub 2016 Aug 22. ACS Chem Biol. 2016. PMID: 27548809

6

Synthesis and cellular activity of stereochemically-pure 2'-O-(2-methoxyethyl)-phosphorothioate oligonucleotides.

Li M, Lightfoot HL, Halloy F, Malinowska AL, Berk C, Behera A, Schümperli D, Hall J. Li M, et al. Among authors: hall j. Chem Commun (Camb). 2017 Jan 3;53(3):541-544. doi: 10.1039/c6cc08473g. Chem Commun (Camb). 2017. PMID: 27966701

7

Type III CRISPR-Cas systems produce cyclic oligoadenylate second messengers.

Niewoehner O, Garcia-Doval C, Rostøl JT, Berk C, Schwede F, Bigler L, Hall J, Marraffini LA, Jinek M. Niewoehner O, et al. Among authors: hall j. Nature. 2017 Aug 31;548(7669):543-548. doi: 10.1038/nature23467. Epub 2017 Jul 19. Nature. 2017. PMID: 28722012

8

Covalent linkage of the DNA repair template to the CRISPR-Cas9 nuclease enhances homology-directed repair.

Savic N, Ringnalda FC, Lindsay H, Berk C, Bargsten K, Li Y, Neri D, Robinson MD, Ciaudo C, Hall J, Jinek M, Schwank G. Savic N, et al. Among authors: hall j. Elife. 2018 May 29;7:e33761. doi: 10.7554/eLife.33761. Elife. 2018. PMID: 29809142 Free PMC article.

9

Noncoding RNAs in disease.

Lekka E, Hall J. Lekka E, et al. Among authors: hall j. FEBS Lett. 2018 Sep;592(17):2884-2900. doi: 10.1002/1873-3468.13182. Epub 2018 Jul 20. FEBS Lett. 2018. PMID: 29972883 Free PMC article. Review.

10

In vitro Generation of CRISPR-Cas9 Complexes with Covalently Bound Repair Templates for Genome Editing in Mammalian Cells.

Savić N, Ringnalda FC, Berk C, Bargsten K, Hall J, Jinek M, Schwank G. Savić N, et al. Among authors: hall j. Bio Protoc. 2019 Jan 5;9(1):e3136. doi: 10.21769/BioProtoc.3136. Bio Protoc. 2019. PMID: 30675496 Free PMC article.

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