Haining WN - Search Results

1

Subsets of exhausted CD8⁺ T cells differentially mediate tumor control and respond to checkpoint blockade.

Miller BC, Sen DR, Al Abosy R, Bi K, Virkud YV, LaFleur MW, Yates KB, Lako A, Felt K, Naik GS, Manos M, Gjini E, Kuchroo JR, Ishizuka JJ, Collier JL, Griffin GK, Maleri S, Comstock DE, Weiss SA, Brown FD, Panda A, Zimmer MD, Manguso RT, Hodi FS, Rodig SJ, Sharpe AH, Haining WN. Miller BC, et al. Among authors: haining wn. Nat Immunol. 2019 Mar;20(3):326-336. doi: 10.1038/s41590-019-0312-6. Epub 2019 Feb 18. Nat Immunol. 2019. PMID: 30778252 Free PMC article.

2

Identification of an evolutionarily conserved transcriptional signature of CD8 memory differentiation that is shared by T and B cells.

Haining WN, Ebert BL, Subrmanian A, Wherry EJ, Eichbaum Q, Evans JW, Mak R, Rivoli S, Pretz J, Angelosanto J, Smutko JS, Walker BD, Kaech SM, Ahmed R, Nadler LM, Golub TR. Haining WN, et al. J Immunol. 2008 Aug 1;181(3):1859-68. doi: 10.4049/jimmunol.181.3.1859. J Immunol. 2008. PMID: 18641323 Free PMC article.

3

Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

Blackburn SD, Shin H, Haining WN, Zou T, Workman CJ, Polley A, Betts MR, Freeman GJ, Vignali DA, Wherry EJ. Blackburn SD, et al. Among authors: haining wn. Nat Immunol. 2009 Jan;10(1):29-37. doi: 10.1038/ni.1679. Epub 2008 Nov 30. Nat Immunol. 2009. PMID: 19043418 Free PMC article.

4

Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF.

Quigley M, Pereyra F, Nilsson B, Porichis F, Fonseca C, Eichbaum Q, Julg B, Jesneck JL, Brosnahan K, Imam S, Russell K, Toth I, Piechocka-Trocha A, Dolfi D, Angelosanto J, Crawford A, Shin H, Kwon DS, Zupkosky J, Francisco L, Freeman GJ, Wherry EJ, Kaufmann DE, Walker BD, Ebert B, Haining WN. Quigley M, et al. Among authors: haining wn. Nat Med. 2010 Oct;16(10):1147-51. doi: 10.1038/nm.2232. Epub 2010 Oct 3. Nat Med. 2010. PMID: 20890291 Free PMC article.

5

CD28 costimulation regulates genome-wide effects on alternative splicing.

Butte MJ, Lee SJ, Jesneck J, Keir ME, Haining WN, Sharpe AH. Butte MJ, et al. Among authors: haining wn. PLoS One. 2012;7(6):e40032. doi: 10.1371/journal.pone.0040032. Epub 2012 Jun 29. PLoS One. 2012. PMID: 22768209 Free PMC article.

6

Isolation of RNA and the synthesis and amplification of cDNA from antigen-specific T cells for genome-wide expression analysis.

Barnitz RA, Imam S, Yates K, Haining WN. Barnitz RA, et al. Among authors: haining wn. Methods Mol Biol. 2013;979:161-73. doi: 10.1007/978-1-62703-290-2_13. Methods Mol Biol. 2013. PMID: 23397395

7

Reversal of in situ T-cell exhaustion during effective human antileukemia responses to donor lymphocyte infusion.

Bachireddy P, Hainz U, Rooney M, Pozdnyakova O, Aldridge J, Zhang W, Liao X, Hodi FS, O'Connell K, Haining WN, Goldstein NR, Canning CM, Soiffer RJ, Ritz J, Hacohen N, Alyea EP 3rd, Kim HT, Wu CJ. Bachireddy P, et al. Among authors: haining wn. Blood. 2014 Feb 27;123(9):1412-21. doi: 10.1182/blood-2013-08-523001. Epub 2013 Dec 19. Blood. 2014. PMID: 24357730 Free PMC article.

8

Strength in numbers: comparing vaccine signatures the modular way.

Haining WN. Haining WN. Nat Immunol. 2014 Feb;15(2):139-41. doi: 10.1038/ni.2807. Nat Immunol. 2014. PMID: 24448573 No abstract available.

9

The transcription factor BATF operates as an essential differentiation checkpoint in early effector CD8+ T cells.

Kurachi M, Barnitz RA, Yosef N, Odorizzi PM, DiIorio MA, Lemieux ME, Yates K, Godec J, Klatt MG, Regev A, Wherry EJ, Haining WN. Kurachi M, et al. Among authors: haining wn. Nat Immunol. 2014 Apr;15(4):373-83. doi: 10.1038/ni.2834. Epub 2014 Mar 2. Nat Immunol. 2014. PMID: 24584090 Free PMC article.

10

Inducible RNAi in vivo reveals that the transcription factor BATF is required to initiate but not maintain CD8+ T-cell effector differentiation.

Godec J, Cowley GS, Barnitz RA, Alkan O, Root DE, Sharpe AH, Haining WN. Godec J, et al. Among authors: haining wn. Proc Natl Acad Sci U S A. 2015 Jan 13;112(2):512-7. doi: 10.1073/pnas.1413291112. Epub 2014 Dec 29. Proc Natl Acad Sci U S A. 2015. PMID: 25548173 Free PMC article.

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