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A genome-scale CRISPR screen reveals PRMT1 as a critical regulator of androgen receptor signaling in prostate cancer.
Tang S, Sethunath V, Metaferia NY, Nogueira MF, Gallant DS, Garner ER, Lairson LA, Penney CM, Li J, Gelbard MK, Alaiwi SA, Seo JH, Hwang JH, Strathdee CA, Baca SC, AbuHammad S, Zhang X, Doench JG, Hahn WC, Takeda DY, Freedman ML, Choi PS, Viswanathan SR. Tang S, et al. Among authors: hahn wc. Cell Rep. 2022 Feb 22;38(8):110417. doi: 10.1016/j.celrep.2022.110417. Cell Rep. 2022. PMID: 35196489 Free PMC article.
Androgen-dependent regulation of Her-2/neu in prostate cancer cells.
Berger R, Lin DI, Nieto M, Sicinska E, Garraway LA, Adams H, Signoretti S, Hahn WC, Loda M. Berger R, et al. Among authors: hahn wc. Cancer Res. 2006 Jun 1;66(11):5723-8. doi: 10.1158/0008-5472.CAN-05-3928. Cancer Res. 2006. PMID: 16740710
Prostate cancer: Re-focusing on androgen receptor signaling.
Nieto M, Finn S, Loda M, Hahn WC. Nieto M, et al. Among authors: hahn wc. Int J Biochem Cell Biol. 2007;39(9):1562-8. doi: 10.1016/j.biocel.2007.01.005. Epub 2007 Jan 20. Int J Biochem Cell Biol. 2007. PMID: 17321194 Free PMC article. Review.
The tumor suppressor PP2A Abeta regulates the RalA GTPase.
Sablina AA, Chen W, Arroyo JD, Corral L, Hector M, Bulmer SE, DeCaprio JA, Hahn WC. Sablina AA, et al. Among authors: hahn wc. Cell. 2007 Jun 1;129(5):969-82. doi: 10.1016/j.cell.2007.03.047. Cell. 2007. PMID: 17540176 Free PMC article.
Integrative genomic approaches identify IKBKE as a breast cancer oncogene.
Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC. Boehm JS, et al. Among authors: hahn wc. Cell. 2007 Jun 15;129(6):1065-79. doi: 10.1016/j.cell.2007.03.052. Cell. 2007. PMID: 17574021 Free article.
AKT-independent signaling downstream of oncogenic PIK3CA mutations in human cancer.
Vasudevan KM, Barbie DA, Davies MA, Rabinovsky R, McNear CJ, Kim JJ, Hennessy BT, Tseng H, Pochanard P, Kim SY, Dunn IF, Schinzel AC, Sandy P, Hoersch S, Sheng Q, Gupta PB, Boehm JS, Reiling JH, Silver S, Lu Y, Stemke-Hale K, Dutta B, Joy C, Sahin AA, Gonzalez-Angulo AM, Lluch A, Rameh LE, Jacks T, Root DE, Lander ES, Mills GB, Hahn WC, Sellers WR, Garraway LA. Vasudevan KM, et al. Among authors: hahn wc. Cancer Cell. 2009 Jul 7;16(1):21-32. doi: 10.1016/j.ccr.2009.04.012. Cancer Cell. 2009. PMID: 19573809 Free PMC article.
Proteomic and genetic approaches identify Syk as an AML target.
Hahn CK, Berchuck JE, Ross KN, Kakoza RM, Clauser K, Schinzel AC, Ross L, Galinsky I, Davis TN, Silver SJ, Root DE, Stone RM, DeAngelo DJ, Carroll M, Hahn WC, Carr SA, Golub TR, Kung AL, Stegmaier K. Hahn CK, et al. Among authors: hahn wc. Cancer Cell. 2009 Oct 6;16(4):281-94. doi: 10.1016/j.ccr.2009.08.018. Cancer Cell. 2009. PMID: 19800574 Free PMC article.
372 results