Haggarty SJ - Search Results

1

Bipolar disorder-iPSC derived neural progenitor cells exhibit dysregulation of store-operated Ca²⁺ entry and accelerated differentiation.

Hewitt T, Alural B, Tilak M, Wang J, Becke N, Chartley E, Perreault M, Haggarty SJ, Sheridan SD, Perlis RH, Jones N, Mellios N, Lalonde J. Hewitt T, et al. Among authors: haggarty sj. Mol Psychiatry. 2023 Dec;28(12):5237-5250. doi: 10.1038/s41380-023-02152-6. Epub 2023 Jul 4. Mol Psychiatry. 2023. PMID: 37402854 Free PMC article.

2

Activity-dependent Regulation of Histone Lysine Demethylase KDM1A by a Putative Thiol/Disulfide Switch.

Ricq EL, Hooker JM, Haggarty SJ. Ricq EL, et al. Among authors: haggarty sj. J Biol Chem. 2016 Nov 18;291(47):24756-24767. doi: 10.1074/jbc.M116.734426. Epub 2016 Sep 15. J Biol Chem. 2016. PMID: 27634040 Free PMC article.

3

Will cell alliance breed bureaucracy and leave contributors out?

Haggarty SJ, Ramalho-Santos M. Haggarty SJ, et al. Nature. 2000 Feb 10;403(6770):591. doi: 10.1038/35001228. Nature. 2000. PMID: 10688171 No abstract available.

4

The Connectivity Map: using gene-expression signatures to connect small molecules, genes, and disease.

Lamb J, Crawford ED, Peck D, Modell JW, Blat IC, Wrobel MJ, Lerner J, Brunet JP, Subramanian A, Ross KN, Reich M, Hieronymus H, Wei G, Armstrong SA, Haggarty SJ, Clemons PA, Wei R, Carr SA, Lander ES, Golub TR. Lamb J, et al. Among authors: haggarty sj. Science. 2006 Sep 29;313(5795):1929-35. doi: 10.1126/science.1132939. Science. 2006. PMID: 17008526

5

Bruton's tyrosine kinase revealed as a negative regulator of Wnt-beta-catenin signaling.

James RG, Biechele TL, Conrad WH, Camp ND, Fass DM, Major MB, Sommer K, Yi X, Roberts BS, Cleary MA, Arthur WT, MacCoss M, Rawlings DJ, Haggarty SJ, Moon RT. James RG, et al. Among authors: haggarty sj. Sci Signal. 2009 May 26;2(72):ra25. doi: 10.1126/scisignal.2000230. Sci Signal. 2009. PMID: 19471023 Free PMC article.

6

Mapping chemical space using molecular descriptors and chemical genetics: deacetylase inhibitors.

Haggarty SJ, Clemons PA, Wong JC, Schreiber SL. Haggarty SJ, et al. Comb Chem High Throughput Screen. 2004 Nov;7(7):669-76. doi: 10.2174/1386207043328319. Comb Chem High Throughput Screen. 2004. PMID: 15578929 Review.

7

SpectralNET--an application for spectral graph analysis and visualization.

Forman JJ, Clemons PA, Schreiber SL, Haggarty SJ. Forman JJ, et al. Among authors: haggarty sj. BMC Bioinformatics. 2005 Oct 19;6:260. doi: 10.1186/1471-2105-6-260. BMC Bioinformatics. 2005. PMID: 16236170 Free PMC article.

8

Inhibitors of class 1 histone deacetylases reverse contextual memory deficits in a mouse model of Alzheimer's disease.

Kilgore M, Miller CA, Fass DM, Hennig KM, Haggarty SJ, Sweatt JD, Rumbaugh G. Kilgore M, et al. Among authors: haggarty sj. Neuropsychopharmacology. 2010 Mar;35(4):870-80. doi: 10.1038/npp.2009.197. Epub 2009 Dec 9. Neuropsychopharmacology. 2010. PMID: 20010553 Free PMC article.

9

Finding new components of the target of rapamycin (TOR) signaling network through chemical genetics and proteome chips.

Huang J, Zhu H, Haggarty SJ, Spring DR, Hwang H, Jin F, Snyder M, Schreiber SL. Huang J, et al. Among authors: haggarty sj. Proc Natl Acad Sci U S A. 2004 Nov 23;101(47):16594-9. doi: 10.1073/pnas.0407117101. Epub 2004 Nov 11. Proc Natl Acad Sci U S A. 2004. PMID: 15539461 Free PMC article.

10

Deregulation of HDAC1 by p25/Cdk5 in neurotoxicity.

Kim D, Frank CL, Dobbin MM, Tsunemoto RK, Tu W, Peng PL, Guan JS, Lee BH, Moy LY, Giusti P, Broodie N, Mazitschek R, Delalle I, Haggarty SJ, Neve RL, Lu Y, Tsai LH. Kim D, et al. Among authors: haggarty sj. Neuron. 2008 Dec 10;60(5):803-17. doi: 10.1016/j.neuron.2008.10.015. Neuron. 2008. PMID: 19081376 Free PMC article.

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