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Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice.
Gregorius J, Wang C, Stambouli O, Hussner T, Qi Y, Tertel T, Börger V, Mohamud Yusuf A, Hagemann N, Yin D, Dittrich R, Mouloud Y, Mairinger FD, Magraoui FE, Popa-Wagner A, Kleinschnitz C, Doeppner TR, Gunzer M, Meyer HE, Giebel B, Hermann DM. Gregorius J, et al. Among authors: hagemann n. Basic Res Cardiol. 2021 Jun 8;116(1):40. doi: 10.1007/s00395-021-00881-9. Basic Res Cardiol. 2021. PMID: 34105014 Free PMC article.
Hyperlipidemia attenuates vascular endothelial growth factor-induced angiogenesis, impairs cerebral blood flow, and disturbs stroke recovery via decreased pericyte coverage of brain endothelial cells.
Zechariah A, ElAli A, Hagemann N, Jin F, Doeppner TR, Helfrich I, Mies G, Hermann DM. Zechariah A, et al. Among authors: hagemann n. Arterioscler Thromb Vasc Biol. 2013 Jul;33(7):1561-7. doi: 10.1161/ATVBAHA.112.300749. Epub 2013 Apr 4. Arterioscler Thromb Vasc Biol. 2013. PMID: 23559636
3D visualization and quantification of microvessels in the whole ischemic mouse brain using solvent-based clearing and light sheet microscopy.
Lugo-Hernandez E, Squire A, Hagemann N, Brenzel A, Sardari M, Schlechter J, Sanchez-Mendoza EH, Gunzer M, Faissner A, Hermann DM. Lugo-Hernandez E, et al. Among authors: hagemann n. J Cereb Blood Flow Metab. 2017 Oct;37(10):3355-3367. doi: 10.1177/0271678X17698970. Epub 2017 Mar 28. J Cereb Blood Flow Metab. 2017. PMID: 28350253 Free PMC article.
Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically Neutrophils.
Wang C, Börger V, Sardari M, Murke F, Skuljec J, Pul R, Hagemann N, Dzyubenko E, Dittrich R, Gregorius J, Hasenberg M, Kleinschnitz C, Popa-Wagner A, Doeppner TR, Gunzer M, Giebel B, Hermann DM. Wang C, et al. Among authors: hagemann n. Stroke. 2020 Jun;51(6):1825-1834. doi: 10.1161/STROKEAHA.119.028012. Epub 2020 Apr 21. Stroke. 2020. PMID: 32312217 Free article.
93 results