Hafkin B - Search Results

1

In Vitro and In Vivo Activities of Contezolid (MRX-I) against Mycobacterium tuberculosis.

Shoen C, DeStefano M, Hafkin B, Cynamon M. Shoen C, et al. Among authors: hafkin b. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00493-18. doi: 10.1128/AAC.00493-18. Print 2018 Aug. Antimicrob Agents Chemother. 2018. PMID: 29784848 Free PMC article.

2

Single- and Multiple-Dose Study To Determine the Safety, Tolerability, Pharmacokinetics, and Food Effect of Oral MRX-I versus Linezolid in Healthy Adult Subjects.

Eckburg PB, Ge Y, Hafkin B. Eckburg PB, et al. Among authors: hafkin b. Antimicrob Agents Chemother. 2017 Mar 24;61(4):e02181-16. doi: 10.1128/AAC.02181-16. Print 2017 Apr. Antimicrob Agents Chemother. 2017. PMID: 28167545 Free PMC article. Clinical Trial.

3

Mode of action, in vitro activity, and in vivo efficacy of AFN-1252, a selective antistaphylococcal FabI inhibitor.

Kaplan N, Albert M, Awrey D, Bardouniotis E, Berman J, Clarke T, Dorsey M, Hafkin B, Ramnauth J, Romanov V, Schmid MB, Thalakada R, Yethon J, Pauls HW. Kaplan N, et al. Among authors: hafkin b. Antimicrob Agents Chemother. 2012 Nov;56(11):5865-74. doi: 10.1128/AAC.01411-12. Epub 2012 Sep 4. Antimicrob Agents Chemother. 2012. PMID: 22948878 Free PMC article.

4

Randomized comparison of linezolid (PNU-100766) versus oxacillin-dicloxacillin for treatment of complicated skin and soft tissue infections.

Stevens DL, Smith LG, Bruss JB, McConnell-Martin MA, Duvall SE, Todd WM, Hafkin B. Stevens DL, et al. Among authors: hafkin b. Antimicrob Agents Chemother. 2000 Dec;44(12):3408-13. doi: 10.1128/AAC.44.12.3408-3413.2000. Antimicrob Agents Chemother. 2000. PMID: 11083648 Free PMC article. Clinical Trial.

5

Hematologic effects of linezolid: summary of clinical experience.

Gerson SL, Kaplan SL, Bruss JB, Le V, Arellano FM, Hafkin B, Kuter DJ. Gerson SL, et al. Among authors: hafkin b. Antimicrob Agents Chemother. 2002 Aug;46(8):2723-6. doi: 10.1128/AAC.46.8.2723-2726.2002. Antimicrob Agents Chemother. 2002. PMID: 12121967 Free PMC article.

6

Efficacy and Safety of AFN-1252, the First Staphylococcus-Specific Antibacterial Agent, in the Treatment of Acute Bacterial Skin and Skin Structure Infections, Including Those in Patients with Significant Comorbidities.

Hafkin B, Kaplan N, Murphy B. Hafkin B, et al. Antimicrob Agents Chemother. 2015 Dec 28;60(3):1695-701. doi: 10.1128/AAC.01741-15. Antimicrob Agents Chemother. 2015. PMID: 26711777 Free PMC article. Clinical Trial.

7

Worldwide assessment of linezolid's clinical safety and tolerability: comparator-controlled phase III studies.

Rubinstein E, Isturiz R, Standiford HC, Smith LG, Oliphant TH, Cammarata S, Hafkin B, Le V, Remington J. Rubinstein E, et al. Among authors: hafkin b. Antimicrob Agents Chemother. 2003 Jun;47(6):1824-31. doi: 10.1128/AAC.47.6.1824-1831.2003. Antimicrob Agents Chemother. 2003. PMID: 12760854 Free PMC article.

8

Pharmacokinetics, pharmacodynamics and efficacy of novel FabI inhibitor AFN-1252 against MSSA and MRSA in the murine thigh infection model.

Banevicius MA, Kaplan N, Hafkin B, Nicolau DP. Banevicius MA, et al. Among authors: hafkin b. J Chemother. 2013 Feb;25(1):26-31. doi: 10.1179/1973947812Y.0000000061. J Chemother. 2013. PMID: 23433441 Free PMC article.

9

AFN-1252, a FabI inhibitor, demonstrates a Staphylococcus-specific spectrum of activity.

Karlowsky JA, Kaplan N, Hafkin B, Hoban DJ, Zhanel GG. Karlowsky JA, et al. Among authors: hafkin b. Antimicrob Agents Chemother. 2009 Aug;53(8):3544-8. doi: 10.1128/AAC.00400-09. Epub 2009 Jun 1. Antimicrob Agents Chemother. 2009. PMID: 19487444 Free PMC article.

10

Safety, tolerability and pharmacokinetics of multiple oral doses of AFN-1252 administered as immediate release (IR) tablets in healthy subjects.

Hunt T, Kaplan N, Hafkin B. Hunt T, et al. Among authors: hafkin b. J Chemother. 2016 Jun;28(3):164-71. doi: 10.1179/1973947815Y.0000000075. Epub 2016 May 13. J Chemother. 2016. PMID: 26431470 Clinical Trial.

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