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MeDIP combined with in-solution targeted enrichment followed by NGS: Inter-individual methylation variability of fetal-specific biomarkers and their implementation in a proof of concept study for NIPT.
Keravnou A, Ioannides M, Loizides C, Tsangaras K, Achilleos A, Mina P, Kypri E, Hadjidaniel MD, Neofytou M, Kyriacou S, Sismani C, Koumbaris G, Patsalis PC. Keravnou A, et al. Among authors: hadjidaniel md. PLoS One. 2018 Jun 11;13(6):e0199010. doi: 10.1371/journal.pone.0199010. eCollection 2018. PLoS One. 2018. PMID: 29889893 Free PMC article.
Bisulfite Conversion of DNA: Performance Comparison of Different Kits and Methylation Quantitation of Epigenetic Biomarkers that Have the Potential to Be Used in Non-Invasive Prenatal Testing.
Leontiou CA, Hadjidaniel MD, Mina P, Antoniou P, Ioannides M, Patsalis PC. Leontiou CA, et al. Among authors: hadjidaniel md. PLoS One. 2015 Aug 6;10(8):e0135058. doi: 10.1371/journal.pone.0135058. eCollection 2015. PLoS One. 2015. PMID: 26247357 Free PMC article.
Whole-genome fetal and maternal DNA methylation analysis using MeDIP-NGS for the identification of differentially methylated regions.
Keravnou A, Ioannides M, Tsangaras K, Loizides C, Hadjidaniel MD, Papageorgiou EA, Kyriakou S, Antoniou P, Mina P, Achilleos A, Neofytou M, Kypri E, Sismani C, Koumbaris G, Patsalis PC. Keravnou A, et al. Among authors: hadjidaniel md. Genet Res (Camb). 2016 Nov 11;98:e15. doi: 10.1017/S0016672316000136. Genet Res (Camb). 2016. PMID: 27834155 Free PMC article.
Combined immune checkpoint blockade increases CD8+CD28+PD-1+ effector T cells and provides a therapeutic strategy for patients with neuroblastoma.
Shirinbak S, Chan RY, Shahani S, Muthugounder S, Kennedy R, Hung LT, Fernandez GE, Hadjidaniel MD, Moghimi B, Sheard MA, Epstein AL, Fabbri M, Shimada H, Asgharzadeh S. Shirinbak S, et al. Among authors: hadjidaniel md. Oncoimmunology. 2021 Jan 4;10(1):1838140. doi: 10.1080/2162402X.2020.1838140. Oncoimmunology. 2021. PMID: 33489468 Free PMC article.
Tumor-associated macrophages promote neuroblastoma via STAT3 phosphorylation and up-regulation of c-MYC.
Hadjidaniel MD, Muthugounder S, Hung LT, Sheard MA, Shirinbak S, Chan RY, Nakata R, Borriello L, Malvar J, Kennedy RJ, Iwakura H, Akamizu T, Sposto R, Shimada H, DeClerck YA, Asgharzadeh S. Hadjidaniel MD, et al. Oncotarget. 2017 Sep 16;8(53):91516-91529. doi: 10.18632/oncotarget.21066. eCollection 2017 Oct 31. Oncotarget. 2017. PMID: 29207662 Free PMC article.