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Dysregulated naive B cells and de novo autoreactivity in severe COVID-19.
Woodruff MC, Ramonell RP, Haddad NS, Anam FA, Rudolph ME, Walker TA, Truong AD, Dixit AN, Han JE, Cabrera-Mora M, Runnstrom MC, Bugrovsky R, Hom J, Connolly EC, Albizua I, Javia V, Cashman KS, Nguyen DC, Kyu S, Singh Saini A, Piazza M, Tipton CM, Khosroshahi A, Gibson G, Martin GS, Maier CL, Esper A, Jenks SA, Lee FE, Sanz I. Woodruff MC, et al. Among authors: haddad ns. Nature. 2022 Nov;611(7934):139-147. doi: 10.1038/s41586-022-05273-0. Epub 2022 Aug 31. Nature. 2022. PMID: 36044993 Free PMC article.
Dominant extrafollicular B cell responses in severe COVID-19 disease correlate with robust viral-specific antibody production but poor clinical outcomes.
Woodruff M, Ramonell R, Cashman K, Nguyen D, Saini A, Haddad N, Ley A, Kyu S, Howell JC, Ozturk T, Lee S, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam F, Sharma M, Wu H, Le S, Jenks S, Tipton CM, Hu W, Lee FE, Sanz I. Woodruff M, et al. medRxiv [Preprint]. 2020 Jun 22:2020.04.29.20083717. doi: 10.1101/2020.04.29.20083717. medRxiv. 2020. PMID: 32511635 Free PMC article. Updated. Preprint.
Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.
Woodruff MC, Ramonell RP, Nguyen DC, Cashman KS, Saini AS, Haddad NS, Ley AM, Kyu S, Howell JC, Ozturk T, Lee S, Suryadevara N, Case JB, Bugrovsky R, Chen W, Estrada J, Morrison-Porter A, Derrico A, Anam FA, Sharma M, Wu HM, Le SN, Jenks SA, Tipton CM, Staitieh B, Daiss JL, Ghosn E, Diamond MS, Carnahan RH, Crowe JE Jr, Hu WT, Lee FE, Sanz I. Woodruff MC, et al. Among authors: haddad ns. Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z. Epub 2020 Oct 7. Nat Immunol. 2020. PMID: 33028979 Free PMC article.
Relaxed peripheral tolerance drives broad de novo autoreactivity in severe COVID-19.
Woodruff MC, Ramonell RP, Saini AS, Haddad NS, Anam FA, Rudolph ME, Bugrovsky R, Hom J, Cashman KS, Nguyen DC, Kyu S, Piazza M, Tipton CM, Jenks SA, Lee FE, Sanz I. Woodruff MC, et al. Among authors: haddad ns. medRxiv [Preprint]. 2021 Jul 27:2020.10.21.20216192. doi: 10.1101/2020.10.21.20216192. medRxiv. 2021. PMID: 33106819 Free PMC article. Updated. Preprint.
Elevated SARS-CoV-2 Antibodies Distinguish Severe Disease in Early COVID-19 Infection.
Haddad NS, Nguyen DC, Kuruvilla ME, Morrison-Porter A, Anam F, Cashman KS, Ramonell RP, Kyu S, Saini AS, Cabrera-Mora M, Derrico A, Alter D, Roback JD, Horwath M, O'Keefe JB, Wu HM, Ian Wong AK, Dretler AW, Gripaldo R, Lane AN, Wu H, Lee S, Hernandez M, Engineer V, Varghese J, Le S, Sanz I, Daiss JL, Eun-Hyung Lee F. Haddad NS, et al. bioRxiv [Preprint]. 2020 Dec 6:2020.12.04.410589. doi: 10.1101/2020.12.04.410589. bioRxiv. 2020. PMID: 33299998 Free PMC article. Preprint.
One-Stop Serum Assay Identifies COVID-19 Disease Severity and Vaccination Responses.
Haddad NS, Nguyen DC, Kuruvilla ME, Morrison-Porter A, Anam F, Cashman KS, Ramonell RP, Kyu S, Saini AS, Cabrera-Mora M, Derrico A, Alter D, Roback JD, Horwath M, O'Keefe JB, Wu HM, Wong AI, Dretler AW, Gripaldo R, Lane AN, Wu H, Chu HY, Lee S, Hernandez M, Engineer V, Varghese J, Patel R, Jalal A, French V, Guysenov I, Lane CE, Mengistsu T, Normile KE, Mnzava O, Le S, Sanz I, Daiss JL, Lee FE. Haddad NS, et al. Immunohorizons. 2021 May 17;5(5):322-335. doi: 10.4049/immunohorizons.2100011. Immunohorizons. 2021. PMID: 34001652 Free PMC article.
Delayed Kinetics of IgG, but Not IgA, Antispike Antibodies in Transplant Recipients following SARS-CoV-2 Infection.
Cravedi P, Ahearn P, Wang L, Yalamarti T, Hartzell S, Azzi Y, Menon MC, Jain A, Billah M, Fernandez-Vina M, Gebel HM, Woodle ES, Haddad NS, Morrison-Porter A, Lee FE, Sanz I, Akalin E, Girnita A, Maltzman JS. Cravedi P, et al. Among authors: haddad ns. J Am Soc Nephrol. 2021 Dec 1;32(12):3221-3230. doi: 10.1681/ASN.2021040573. Epub 2021 Dec 1. J Am Soc Nephrol. 2021. PMID: 34599041 Free PMC article.
Inactivation of SARS-CoV-2 and COVID-19 Patient Samples for Contemporary Immunology and Metabolomics Studies.
Eddins DJ, Bassit LC, Chandler JD, Haddad NS, Musall KL, Yang J, Kosters A, Dobosh BS, Hernández MR, Ramonell RP, Tirouvanziam RM, Lee FE, Zandi K, Schinazi RF, Ghosn EEB. Eddins DJ, et al. Among authors: haddad ns. Immunohorizons. 2022 Feb 16;6(2):144-155. doi: 10.4049/immunohorizons.2200005. Immunohorizons. 2022. PMID: 35173021 Free PMC article.
40 results