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Page 1
Shotgun metagenomics and systemic targeted metabolomics highlight indole-3-propionic acid as a protective gut microbial metabolite against influenza infection.
Heumel S, de Rezende Rodovalho V, Urien C, Specque F, Brito Rodrigues P, Robil C, Delval L, Sencio V, Descat A, Deruyter L, Ferreira S, Gomes Machado M, Barthelemy A, Angulo FS, Haas JT, Goosens JF, Wolowczuk I, Grangette C, Rouillé Y, Grimaud G, Lenski M, Hennart B, Ramirez Vinolo MA, Trottein F. Heumel S, et al. Among authors: haas jt. Gut Microbes. 2024 Jan-Dec;16(1):2325067. doi: 10.1080/19490976.2024.2325067. Epub 2024 Mar 6. Gut Microbes. 2024. PMID: 38445660 Free PMC article.
Roux-en-Y gastric bypass induces hepatic transcriptomic signatures and plasma metabolite changes indicative of improved cholesterol homeostasis.
Lalloyer F, Mogilenko DA, Verrijken A, Haas JT, Lamazière A, Kouach M, Descat A, Caron S, Vallez E, Derudas B, Gheeraert C, Baugé E, Despres G, Dirinck E, Tailleux A, Dombrowicz D, Van Gaal L, Eeckhoute J, Lefebvre P, Goossens JF, Francque S, Staels B. Lalloyer F, et al. Among authors: haas jt. J Hepatol. 2023 Oct;79(4):898-909. doi: 10.1016/j.jhep.2023.05.012. Epub 2023 May 23. J Hepatol. 2023. PMID: 37230231
Adipocyte-specific FXR-deficiency protects adipose tissue from oxidative stress and insulin resistance and improves glucose homeostasis.
Dehondt H, Marino A, Butruille L, Mogilenko DA, Nzoussi Loubota AC, Chávez-Talavera O, Dorchies E, Vallez E, Haas J, Derudas B, Bongiovanni A, Tardivel M, Kuipers F, Lefebvre P, Lestavel S, Tailleux A, Dombrowicz D, Caron S, Staels B. Dehondt H, et al. Mol Metab. 2023 Mar;69:101686. doi: 10.1016/j.molmet.2023.101686. Epub 2023 Feb 4. Mol Metab. 2023. PMID: 36746333 Free PMC article.
Time-of-day-dependent variation of the human liver transcriptome and metabolome is disrupted in MASLD.
Johanns M, Haas JT, Raverdy V, Vandel J, Chevalier-Dubois J, Guille L, Derudas B, Legendre B, Caiazzo R, Verkindt H, Gnemmi V, Leteurtre E, Derhourhi M, Bonnefond A, Froguel P, Eeckhoute J, Lassailly G, Mathurin P, Pattou F, Staels B, Lefebvre P. Johanns M, et al. Among authors: haas jt. JHEP Rep. 2023 Oct 27;6(1):100948. doi: 10.1016/j.jhepr.2023.100948. eCollection 2024 Jan. JHEP Rep. 2023. PMID: 38125300 Free PMC article.
Hematopoietic Somatic Mosaicism Is Associated With an Increased Risk of Postoperative Atrial Fibrillation.
Ninni S, Dombrowicz D, Kuznetsova T, Vicario R, Gao V, Molendi-Coste O, Haas J, Woitrain E, Coisne A, Neele AE, Prange K, Willemsen L, Aghezzaf S, Fragkogianni S, Tazibet A, Pineau L, White JR, Eeckhoute J, Koussa M, Dubrulle H, Juthier F, Soquet J, Vincentelli A, Edme JL, de Winther M, Geissmann F, Staels B, Montaigne D. Ninni S, et al. J Am Coll Cardiol. 2023 Apr 4;81(13):1263-1278. doi: 10.1016/j.jacc.2023.01.036. J Am Coll Cardiol. 2023. PMID: 36990546 Free PMC article.
The tissue-specific metabolic effects of the PPARα agonist ciprofibrate in insulin-resistant male individuals: a double-blind, randomized, placebo-controlled crossover study.
de Wit-Verheggen VHW, Vanweert F, Raiko J, Liénard V, Schaart G, Gemmink A, Nascimento EBM, Hesselink MKC, Wildberger JE, Wierts R, Joris PJ, Haas J, Montaigne D, Staels B, Phielix E, Schrauwen P, Schrauwen-Hinderling VB, van de Weijer T. de Wit-Verheggen VHW, et al. Obesity (Silver Spring). 2023 Oct;31(10):2493-2504. doi: 10.1002/oby.23874. Epub 2023 Sep 5. Obesity (Silver Spring). 2023. PMID: 37670579 Clinical Trial.
The ubiquitin-like modifier FAT10 is induced in MASLD and impairs the lipid-regulatory activity of PPARα.
Clavreul L, Bernard L, Cotte AK, Hennuyer N, Bourouh C, Devos C, Helleboid A, Haas JT, Verrijken A, Gheeraert C, Derudas B, Guille L, Chevalier J, Eeckhoute J, Vallez E, Dorchies E, Van Gaal L, Lassailly G, Francque S, Staels B, Paumelle R. Clavreul L, et al. Among authors: haas jt. Metabolism. 2024 Feb;151:155720. doi: 10.1016/j.metabol.2023.155720. Epub 2023 Nov 3. Metabolism. 2024. PMID: 37926201
Functional genomics uncovers the transcription factor BNC2 as required for myofibroblastic activation in fibrosis.
Bobowski-Gerard M, Boulet C, Zummo FP, Dubois-Chevalier J, Gheeraert C, Bou Saleh M, Strub JM, Farce A, Ploton M, Guille L, Vandel J, Bongiovanni A, Very N, Woitrain E, Deprince A, Lalloyer F, Bauge E, Ferri L, Ntandja-Wandji LC, Cotte AK, Grangette C, Vallez E, Cianférani S, Raverdy V, Caiazzo R, Gnemmi V, Leteurtre E, Pourcet B, Paumelle R, Ravnskjaer K, Lassailly G, Haas JT, Mathurin P, Pattou F, Dubuquoy L, Staels B, Lefebvre P, Eeckhoute J. Bobowski-Gerard M, et al. Among authors: haas jt. Nat Commun. 2022 Sep 10;13(1):5324. doi: 10.1038/s41467-022-33063-9. Nat Commun. 2022. PMID: 36088459 Free PMC article.
Apolipoprotein F is reduced in humans with steatosis and controls plasma triglyceride-rich lipoprotein metabolism.
Deprince A, Hennuyer N, Kooijman S, Pronk ACM, Baugé E, Lienard V, Verrijken A, Dirinck E, Vonghia L, Woitrain E, Kloosterhuis NJ, Marez E, Jacquemain P, Wolters JC, Lalloyer F, Eberlé D, Quemener S, Vallez E, Tailleux A, Kouach M, Goossens JF, Raverdy V, Derudas B, Kuivenhoven JA, Croyal M, van de Sluis B, Francque S, Pattou F, Rensen PCN, Staels B, Haas JT. Deprince A, et al. Among authors: haas jt. Hepatology. 2023 Apr 1;77(4):1287-1302. doi: 10.1002/hep.32631. Epub 2022 Jul 15. Hepatology. 2023. PMID: 35735979 Free PMC article.
47 results