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TGFβ promotes fibrosis by MYST1-dependent epigenetic regulation of autophagy.
Zehender A, Li YN, Lin NY, Stefanica A, Nüchel J, Chen CW, Hsu HH, Zhu H, Ding X, Huang J, Shen L, Györfi AH, Soare A, Rauber S, Bergmann C, Ramming A, Plomann M, Eckes B, Schett G, Distler JHW. Zehender A, et al. Among authors: gyorfi ah. Nat Commun. 2021 Jul 20;12(1):4404. doi: 10.1038/s41467-021-24601-y. Nat Commun. 2021. PMID: 34285225 Free PMC article.
The tyrosine phosphatase SHP2 controls TGFβ-induced STAT3 signaling to regulate fibroblast activation and fibrosis.
Zehender A, Huang J, Györfi AH, Matei AE, Trinh-Minh T, Xu X, Li YN, Chen CW, Lin J, Dees C, Beyer C, Gelse K, Zhang ZY, Bergmann C, Ramming A, Birchmeier W, Distler O, Schett G, Distler JHW. Zehender A, et al. Among authors: gyorfi ah. Nat Commun. 2018 Aug 14;9(1):3259. doi: 10.1038/s41467-018-05768-3. Nat Commun. 2018. PMID: 30108215 Free PMC article.
Vascularised human skin equivalents as a novel in vitro model of skin fibrosis and platform for testing of antifibrotic drugs.
Matei AE, Chen CW, Kiesewetter L, Györfi AH, Li YN, Trinh-Minh T, Xu X, Tran Manh C, van Kuppevelt T, Hansmann J, Jüngel A, Schett G, Groeber-Becker F, Distler JHW. Matei AE, et al. Among authors: gyorfi ah. Ann Rheum Dis. 2019 Dec;78(12):1686-1692. doi: 10.1136/annrheumdis-2019-216108. Epub 2019 Sep 20. Ann Rheum Dis. 2019. PMID: 31540936
Shared and distinct mechanisms of fibrosis.
Distler JHW, Györfi AH, Ramanujam M, Whitfield ML, Königshoff M, Lafyatis R. Distler JHW, et al. Among authors: gyorfi ah. Nat Rev Rheumatol. 2019 Dec;15(12):705-730. doi: 10.1038/s41584-019-0322-7. Epub 2019 Nov 11. Nat Rev Rheumatol. 2019. PMID: 31712723 Review.
PGC-1α regulates autophagy to promote fibroblast activation and tissue fibrosis.
Zhang Y, Shen L, Zhu H, Dreissigacker K, Distler D, Zhou X, Györfi AH, Bergmann C, Meng X, Dees C, Trinh-Minh T, Ludolph I, Horch R, Ramming A, Schett G, Distler JHW. Zhang Y, et al. Among authors: gyorfi ah. Ann Rheum Dis. 2020 Sep;79(9):1227-1233. doi: 10.1136/annrheumdis-2020-216963. Epub 2020 Jun 1. Ann Rheum Dis. 2020. PMID: 32482644
Glucocorticoid-induced relapse of COVID-19 in a patient with sarcoidosis.
Györfi AH, Kopp M, May M, Vetter M, Uder M, Kremer AE, Schett G, Harrer T, Distler JHW. Györfi AH, et al. Ann Rheum Dis. 2021 Jun;80(6):e87. doi: 10.1136/annrheumdis-2020-218258. Epub 2020 Jun 30. Ann Rheum Dis. 2021. PMID: 32606044 No abstract available.
X-linked inhibitor of apoptosis protein (XIAP) inhibition in systemic sclerosis (SSc).
Bergmann C, Hallenberger L, Chenguiti Fakhouri S, Merlevede B, Brandt A, Dees C, Zhu H, Zehender A, Zhou X, Schwab A, Chen CW, Györfi AH, Matei AE, Chakraborty D, Trinh-Minh T, Rauber S, Coras R, Bozec A, Kreuter A, Ziemer M, Schett G, Distler JHW. Bergmann C, et al. Among authors: gyorfi ah. Ann Rheum Dis. 2021 Aug;80(8):1048-1056. doi: 10.1136/annrheumdis-2020-219822. Epub 2021 Apr 26. Ann Rheum Dis. 2021. PMID: 33903093
26 results