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532 results

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Redirecting extracellular proteases to molecularly guide radiosensitizing drugs to tumors.
Hingorani DV, Crisp JL, Doan MK, Camargo MF, Quraishi MA, Aguilera J, Gilardi M, Gross LA, Jiang T, Li WT, Ongkeko WM, Cohen EEW, Gutkind JS, Adams SR, Advani SJ. Hingorani DV, et al. Among authors: gutkind js. Biomaterials. 2020 Jul;248:120032. doi: 10.1016/j.biomaterials.2020.120032. Epub 2020 Apr 11. Biomaterials. 2020. PMID: 32304937 Free PMC article.
4E-BP1 Is a Tumor Suppressor Protein Reactivated by mTOR Inhibition in Head and Neck Cancer.
Wang Z, Feng X, Molinolo AA, Martin D, Vitale-Cross L, Nohata N, Ando M, Wahba A, Amornphimoltham P, Wu X, Gilardi M, Allevato M, Wu V, Steffen DJ, Tofilon P, Sonenberg N, Califano J, Chen Q, Lippman SM, Gutkind JS. Wang Z, et al. Among authors: gutkind js. Cancer Res. 2019 Apr 1;79(7):1438-1450. doi: 10.1158/0008-5472.CAN-18-1220. Epub 2019 Mar 20. Cancer Res. 2019. PMID: 30894372 Free PMC article.
Syngeneic animal models of tobacco-associated oral cancer reveal the activity of in situ anti-CTLA-4.
Wang Z, Wu VH, Allevato MM, Gilardi M, He Y, Luis Callejas-Valera J, Vitale-Cross L, Martin D, Amornphimoltham P, Mcdermott J, Yung BS, Goto Y, Molinolo AA, Sharabi AB, Cohen EEW, Chen Q, Lyons JG, Alexandrov LB, Gutkind JS. Wang Z, et al. Among authors: gutkind js. Nat Commun. 2019 Dec 5;10(1):5546. doi: 10.1038/s41467-019-13471-0. Nat Commun. 2019. PMID: 31804466 Free PMC article.
Tipifarnib as a Precision Therapy for HRAS-Mutant Head and Neck Squamous Cell Carcinomas.
Gilardi M, Wang Z, Proietto M, Chillà A, Calleja-Valera JL, Goto Y, Vanoni M, Janes MR, Mikulski Z, Gualberto A, Molinolo AA, Ferrara N, Gutkind JS, Burrows F. Gilardi M, et al. Among authors: gutkind js. Mol Cancer Ther. 2020 Sep;19(9):1784-1796. doi: 10.1158/1535-7163.MCT-19-0958. Epub 2020 Jul 29. Mol Cancer Ther. 2020. PMID: 32727882 Free PMC article.
HPV E2, E4, E5 drive alternative carcinogenic pathways in HPV positive cancers.
Ren S, Gaykalova DA, Guo T, Favorov AV, Fertig EJ, Tamayo P, Callejas-Valera JL, Allevato M, Gilardi M, Santos J, Fukusumi T, Sakai A, Ando M, Sadat S, Liu C, Xu G, Fisch KM, Wang Z, Molinolo AA, Gutkind JS, Ideker T, Koch WM, Califano JA. Ren S, et al. Among authors: gutkind js. Oncogene. 2020 Oct;39(40):6327-6339. doi: 10.1038/s41388-020-01431-8. Epub 2020 Aug 26. Oncogene. 2020. PMID: 32848210 Free PMC article.
532 results