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Noncanonical β-catenin interactions promote leukemia-initiating activity in early T-cell acute lymphoblastic leukemia.
Panelli P, De Santis E, Colucci M, Tamiro F, Sansico F, Miroballo M, Murgo E, Padovano C, Gusscott S, Ciavarella M, Chavez EA, Bianchi F, Rossi G, Carella AM, Steidl C, Weng AP, Giambra V. Panelli P, et al. Among authors: gusscott s. Blood. 2023 Mar 30;141(13):1597-1609. doi: 10.1182/blood.2022017079. Blood. 2023. PMID: 36315912 Free PMC article.
Leukemia stem cells in T-ALL require active Hif1α and Wnt signaling.
Giambra V, Jenkins CE, Lam SH, Hoofd C, Belmonte M, Wang X, Gusscott S, Gracias D, Weng AP. Giambra V, et al. Among authors: gusscott s. Blood. 2015 Jun 18;125(25):3917-27. doi: 10.1182/blood-2014-10-609370. Epub 2015 May 1. Blood. 2015. PMID: 25934477 Free PMC article.
Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity.
Giambra V, Gusscott S, Gracias D, Song R, Lam SH, Panelli P, Tyshchenko K, Jenkins CE, Hoofd C, Lorzadeh A, Carles A, Hirst M, Eaves CJ, Weng AP. Giambra V, et al. Among authors: gusscott s. Cell Stem Cell. 2018 Nov 1;23(5):714-726.e7. doi: 10.1016/j.stem.2018.08.018. Epub 2018 Sep 27. Cell Stem Cell. 2018. PMID: 30269902 Free article.
Synthetic modeling reveals HOXB genes are critical for the initiation and maintenance of human leukemia.
Kusakabe M, Sun AC, Tyshchenko K, Wong R, Nanda A, Shanna C, Gusscott S, Chavez EA, Lorzadeh A, Zhu A, Hill A, Hung S, Brown S, Babaian A, Wang X, Holt RA, Steidl C, Karsan A, Humphries RK, Eaves CJ, Hirst M, Weng AP. Kusakabe M, et al. Among authors: gusscott s. Nat Commun. 2019 Jul 2;10(1):2913. doi: 10.1038/s41467-019-10510-8. Nat Commun. 2019. PMID: 31266935 Free PMC article.
15 results