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Uncompetitive nanomolar dimeric indenoindole inhibitors of the human breast cancer resistance pump ABCG2.
Eur J Med Chem. 2021 Feb 5;211:113017. doi: 10.1016/j.ejmech.2020.113017. Epub 2020 Nov 12.
Eur J Med Chem. 2021.
PMID: 33223263
Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and non-toxic inhibitors stimulating basal ATPase activity.
Gozzi GJ, Bouaziz Z, Winter E, Daflon-Yunes N, Honorat M, Guragossian N, Marminon C, Valdameri G, Bollacke A, Guillon J, Pinaud N, Marchivie M, Cadena SM, Jose J, Le Borgne M, Di Pietro A.
Gozzi GJ, et al. Among authors: guragossian n.
Drug Des Devel Ther. 2015 Jul 3;9:3481-95. doi: 10.2147/DDDT.S84982. eCollection 2015.
Drug Des Devel Ther. 2015.
PMID: 26170632
Free PMC article.
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New, highly potent and non-toxic, chromone inhibitors of the human breast cancer resistance protein ABCG2.
Pires ADRA, Lecerf-Schmidt F, Guragossian N, Pazinato J, Gozzi GJ, Winter E, Valdameri G, Veale A, Boumendjel A, Di Pietro A, Pérès B.
Pires ADRA, et al. Among authors: guragossian n.
Eur J Med Chem. 2016 Oct 21;122:291-301. doi: 10.1016/j.ejmech.2016.05.053. Epub 2016 Jun 27.
Eur J Med Chem. 2016.
PMID: 27376492
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Structure-based design and profiling of novel 17β-HSD14 inhibitors.
Braun F, Bertoletti N, Möller G, Adamski J, Frotscher M, Guragossian N, Madeira Gírio PA, Le Borgne M, Ettouati L, Falson P, Müller S, Vollmer G, Heine A, Klebe G, Marchais-Oberwinkler S.
Braun F, et al. Among authors: guragossian n.
Eur J Med Chem. 2018 Jul 15;155:61-76. doi: 10.1016/j.ejmech.2018.05.029. Epub 2018 May 22.
Eur J Med Chem. 2018.
PMID: 29859505
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Mechanistic basis of breast cancer resistance protein inhibition by new indeno[1,2-b]indoles.
Kita DH, Guragossian N, Zattoni IF, Moure VR, Rego FGM, Lusvarghi S, Moulenat T, Belhani B, Picheth G, Bouacida S, Bouaziz Z, Marminon C, Berredjem M, Jose J, Gonçalves MB, Ambudkar SV, Valdameri G, Le Borgne M.
Kita DH, et al. Among authors: guragossian n.
Sci Rep. 2021 Jan 19;11(1):1788. doi: 10.1038/s41598-020-79892-w.
Sci Rep. 2021.
PMID: 33469044
Free PMC article.
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