Gumeni S - Search Results

1

Elastase inhibitory activity of secondary metabolites from the fungus Virgaria nigra CF-231658.

Samy MN, Le Goff G, Lopes P, Georgousaki K, Gumeni S, Almeida C, Gonzalez-Menendez V, Genilloud O, Trougakos IP, Fokialakis N, Ouazzani J. Samy MN, et al. Among authors: gumeni s. Nat Prod Res. 2022 Mar;36(6):1668-1671. doi: 10.1080/14786419.2021.1899175. Epub 2021 Mar 11. Nat Prod Res. 2022. PMID: 33706628

2

Cross Talk of Proteostasis and Mitostasis in Cellular Homeodynamics, Ageing, and Disease.

Gumeni S, Trougakos IP. Gumeni S, et al. Oxid Med Cell Longev. 2016;2016:4587691. doi: 10.1155/2016/4587691. Epub 2016 Feb 9. Oxid Med Cell Longev. 2016. PMID: 26977249 Free PMC article. Review.

3

Proteome Stability as a Key Factor of Genome Integrity.

Gumeni S, Evangelakou Z, Gorgoulis VG, Trougakos IP. Gumeni S, et al. Int J Mol Sci. 2017 Sep 22;18(10):2036. doi: 10.3390/ijms18102036. Int J Mol Sci. 2017. PMID: 28937603 Free PMC article. Review.

4

Hyperactivation of Nrf2 increases stress tolerance at the cost of aging acceleration due to metabolic deregulation.

Tsakiri EN, Gumeni S, Iliaki KK, Benaki D, Vougas K, Sykiotis GP, Gorgoulis VG, Mikros E, Scorrano L, Trougakos IP. Tsakiri EN, et al. Among authors: gumeni s. Aging Cell. 2019 Feb;18(1):e12845. doi: 10.1111/acel.12845. Epub 2018 Dec 10. Aging Cell. 2019. PMID: 30537423 Free PMC article.

5

Proteasome dysfunction induces excessive proteome instability and loss of mitostasis that can be mitigated by enhancing mitochondrial fusion or autophagy.

Tsakiri EN, Gumeni S, Vougas K, Pendin D, Papassideri I, Daga A, Gorgoulis V, Juhász G, Scorrano L, Trougakos IP. Tsakiri EN, et al. Among authors: gumeni s. Autophagy. 2019 Oct;15(10):1757-1773. doi: 10.1080/15548627.2019.1596477. Epub 2019 Apr 19. Autophagy. 2019. PMID: 31002009 Free PMC article.

6

Nutrigenomics as a tool to study the impact of diet on aging and age-related diseases: the Drosophila approach.

Evangelakou Z, Manola M, Gumeni S, Trougakos IP. Evangelakou Z, et al. Among authors: gumeni s. Genes Nutr. 2019 May 2;14:12. doi: 10.1186/s12263-019-0638-6. eCollection 2019. Genes Nutr. 2019. PMID: 31073342 Free PMC article. Review.

7

Functional wiring of proteostatic and mitostatic modules ensures transient organismal survival during imbalanced mitochondrial dynamics.

Gumeni S, Evangelakou Z, Tsakiri EN, Scorrano L, Trougakos IP. Gumeni S, et al. Redox Biol. 2019 Jun;24:101219. doi: 10.1016/j.redox.2019.101219. Epub 2019 May 17. Redox Biol. 2019. PMID: 31132524 Free PMC article.

8

Cercospora sp. as a source of anti-aging polyketides targeting 26S proteasome and scale-up production in submerged bioreactor.

Georgousaki K, Tsafantakis N, Gumeni S, González-Menéndez V, de Pedro N, Tormo JR, Almeida C, Lambert C, Genilloud O, Trougakos IP, Fokialakis N. Georgousaki K, et al. Among authors: gumeni s. J Biotechnol. 2019 Aug 10;301:88-96. doi: 10.1016/j.jbiotec.2019.05.015. Epub 2019 May 29. J Biotechnol. 2019. PMID: 31152756

9

Osmanicin, a Polyketide Alkaloid Isolated from Streptomyces osmaniensis CA-244599 Inhibits Elastase in Human Fibroblasts.

Samy MN, Le Goff G, Lopes P, Georgousaki K, Gumeni S, Almeida C, González I, Genilloud O, Trougakos I, Fokialakis N, Ouazzani J. Samy MN, et al. Among authors: gumeni s. Molecules. 2019 Jun 15;24(12):2239. doi: 10.3390/molecules24122239. Molecules. 2019. PMID: 31208056 Free PMC article.

10

Screening for tyrosinase inhibitors from actinomycetes; identification of trichostatin derivatives from Streptomyces sp. CA-129531 and scale up production in bioreactor.

Georgousaki K, Tsafantakis N, Gumeni S, Gonzalez I, Mackenzie TA, Reyes F, Lambert C, Trougakos IP, Genilloud O, Fokialakis N. Georgousaki K, et al. Among authors: gumeni s. Bioorg Med Chem Lett. 2020 Mar 15;30(6):126952. doi: 10.1016/j.bmcl.2020.126952. Epub 2020 Jan 21. Bioorg Med Chem Lett. 2020. PMID: 32005414

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