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Species-agnostic polymeric formulations for inhalable messenger RNA delivery to the lung.
Rotolo L, Vanover D, Bruno NC, Peck HE, Zurla C, Murray J, Noel RK, O'Farrell L, Araínga M, Orr-Burks N, Joo JY, Chaves LCS, Jung Y, Beyersdorf J, Gumber S, Guerrero-Ferreira R, Cornejo S, Thoresen M, Olivier AK, Kuo KM, Gumbart JC, Woolums AR, Villinger F, Lafontaine ER, Hogan RJ, Finn MG, Santangelo PJ. Rotolo L, et al. Among authors: gumber s. Nat Mater. 2023 Mar;22(3):369-379. doi: 10.1038/s41563-022-01404-0. Epub 2022 Nov 28. Nat Mater. 2023. PMID: 36443576
Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy-treated macaques.
Santangelo PJ, Rogers KA, Zurla C, Blanchard EL, Gumber S, Strait K, Connor-Stroud F, Schuster DM, Amancha PK, Hong JJ, Byrareddy SN, Hoxie JA, Vidakovic B, Ansari AA, Hunter E, Villinger F. Santangelo PJ, et al. Among authors: gumber s. Nat Methods. 2015 May;12(5):427-32. doi: 10.1038/nmeth.3320. Epub 2015 Mar 9. Nat Methods. 2015. PMID: 25751144 Free PMC article.
Induction of Th1-Biased T Follicular Helper (Tfh) Cells in Lymphoid Tissues during Chronic Simian Immunodeficiency Virus Infection Defines Functionally Distinct Germinal Center Tfh Cells.
Velu V, Mylvaganam GH, Gangadhara S, Hong JJ, Iyer SS, Gumber S, Ibegbu CC, Villinger F, Amara RR. Velu V, et al. Among authors: gumber s. J Immunol. 2016 Sep 1;197(5):1832-42. doi: 10.4049/jimmunol.1600143. Epub 2016 Aug 1. J Immunol. 2016. PMID: 27481845 Free PMC article.
Sustained virologic control in SIV+ macaques after antiretroviral and α4β7 antibody therapy.
Byrareddy SN, Arthos J, Cicala C, Villinger F, Ortiz KT, Little D, Sidell N, Kane MA, Yu J, Jones JW, Santangelo PJ, Zurla C, McKinnon LR, Arnold KB, Woody CE, Walter L, Roos C, Noll A, Van Ryk D, Jelicic K, Cimbro R, Gumber S, Reid MD, Adsay V, Amancha PK, Mayne AE, Parslow TG, Fauci AS, Ansari AA. Byrareddy SN, et al. Among authors: gumber s. Science. 2016 Oct 14;354(6309):197-202. doi: 10.1126/science.aag1276. Science. 2016. PMID: 27738167 Free PMC article.
Hypo-osmolar Formulation of Tenofovir (TFV) Enema Promotes Uptake and Metabolism of TFV in Tissues, Leading to Prevention of SHIV/SIV Infection.
Xiao P, Gumber S, Marzinke MA, Date AA, Hoang T, Hanes J, Ensign LM, Wang L, Rohan L, Fuchs EJ, Hendrix C, Villinger F. Xiao P, et al. Among authors: gumber s. Antimicrob Agents Chemother. 2017 Dec 21;62(1):e01644-17. doi: 10.1128/AAC.01644-17. Print 2018 Jan. Antimicrob Agents Chemother. 2017. PMID: 29084755 Free PMC article.
Early treatment of SIV+ macaques with an α4β7 mAb alters virus distribution and preserves CD4+ T cells in later stages of infection.
Santangelo PJ, Cicala C, Byrareddy SN, Ortiz KT, Little D, Lindsay KE, Gumber S, Hong JJ, Jelicic K, Rogers KA, Zurla C, Villinger F, Ansari AA, Fauci AS, Arthos J. Santangelo PJ, et al. Among authors: gumber s. Mucosal Immunol. 2018 May;11(3):932-946. doi: 10.1038/mi.2017.112. Epub 2017 Dec 20. Mucosal Immunol. 2018. PMID: 29346349 Free PMC article.
109 results