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Restoration of tumor suppression in prostate cancer by targeting the E3 ligase E6AP.
Paul PJ, Raghu D, Chan AL, Gulati T, Lambeth L, Takano E, Herold MJ, Hagekyriakou J, Vessella RL, Fedele C, Shackleton M, Williams ED, Fox S, Williams S, Haupt S, Gamell C, Haupt Y. Paul PJ, et al. Among authors: gulati t. Oncogene. 2016 Dec 1;35(48):6235-6245. doi: 10.1038/onc.2016.159. Epub 2016 Sep 19. Oncogene. 2016. PMID: 27641331
E6AP Promotes a Metastatic Phenotype in Prostate Cancer.
Gamell C, Bandilovska I, Gulati T, Kogan A, Lim SC, Kovacevic Z, Takano EA, Timpone C, Agupitan AD, Litchfield C, Blandino G, Horvath LG, Fox SB, Williams SG, Russo A, Gallo E, Paul PJ, Mitchell C, Sandhu S, Keam SP, Haupt S, Richardson DR, Haupt Y. Gamell C, et al. Among authors: gulati t. iScience. 2019 Dec 20;22:1-15. doi: 10.1016/j.isci.2019.10.065. Epub 2019 Nov 2. iScience. 2019. PMID: 31739170 Free PMC article.
Reduced abundance of the E3 ubiquitin ligase E6AP contributes to decreased expression of the INK4/ARF locus in non-small cell lung cancer.
Gamell C, Gulati T, Levav-Cohen Y, Young RJ, Do H, Pilling P, Takano E, Watkins N, Fox SB, Russell P, Ginsberg D, Monahan BJ, Wright G, Dobrovic A, Haupt S, Solomon B, Haupt Y. Gamell C, et al. Among authors: gulati t. Sci Signal. 2017 Jan 10;10(461):eaaf8223. doi: 10.1126/scisignal.aaf8223. Sci Signal. 2017. PMID: 28074012
E6AP promotes prostate cancer by reducing p27 expression.
Raghu D, Paul PJ, Gulati T, Deb S, Khoo C, Russo A, Gallo E, Blandino G, Chan AL, Takano E, Sandhu SK, Fox SB, Williams S, Haupt S, Gamell C, Haupt Y. Raghu D, et al. Among authors: gulati t. Oncotarget. 2017 Jun 27;8(26):42939-42948. doi: 10.18632/oncotarget.17224. Oncotarget. 2017. PMID: 28477016 Free PMC article.
Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC.
Grohmann M, Wiede F, Dodd GT, Gurzov EN, Ooi GJ, Butt T, Rasmiena AA, Kaur S, Gulati T, Goh PK, Treloar AE, Archer S, Brown WA, Muller M, Watt MJ, Ohara O, McLean CA, Tiganis T. Grohmann M, et al. Among authors: gulati t. Cell. 2018 Nov 15;175(5):1289-1306.e20. doi: 10.1016/j.cell.2018.09.053. Epub 2018 Oct 25. Cell. 2018. PMID: 30454647 Free PMC article.
45 results