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Chronic myeloid leukemia progenitor cells require autophagy when leaving hypoxia-induced quiescence.
Ianniciello A, Dumas PY, Drullion C, Guitart A, Villacreces A, Peytour Y, Chevaleyre J, Brunet de la Grange P, Vigon I, Desplat V, Priault M, Sbarba PD, Ivanovic Z, Mahon FX, Pasquet JM. Ianniciello A, et al. Oncotarget. 2017 Jun 30;8(57):96984-96992. doi: 10.18632/oncotarget.18904. eCollection 2017 Nov 14. Oncotarget. 2017. PMID: 29228587 Free PMC article.
Ca2+tapulting HSCs into action.
Guitart AV, Finch AJ, Kranc KR. Guitart AV, et al. J Exp Med. 2018 Aug 6;215(8):1971-1973. doi: 10.1084/jem.20181097. Epub 2018 Jul 12. J Exp Med. 2018. PMID: 30002075 Free PMC article.
Hematopoietic niche drives FLT3-ITD acute myeloid leukemia resistance to quizartinib via STAT5-and hypoxia-dependent upregulation of AXL.
Dumas PY, Naudin C, Martin-Lannerée S, Izac B, Casetti L, Mansier O, Rousseau B, Artus A, Dufossée M, Giese A, Dubus P, Pigneux A, Praloran V, Bidet A, Villacreces A, Guitart A, Milpied N, Kosmider O, Vigon I, Desplat V, Dusanter-Fourt I, Pasquet JM. Dumas PY, et al. Haematologica. 2019 Oct;104(10):2017-2027. doi: 10.3324/haematol.2018.205385. Epub 2019 Mar 28. Haematologica. 2019. PMID: 30923103 Free PMC article. Clinical Trial.
α-Tocopherol Attenuates Oxidative Phosphorylation of CD34+ Cells, Enhances Their G0 Phase Fraction and Promotes Hematopoietic Stem and Primitive Progenitor Cell Maintenance.
Rodriguez L, Duchez P, Touya N, Debeissat C, Guitart AV, Pasquet JM, Vlaski-Lafarge M, Brunet de la Grange P, Ivanovic Z. Rodriguez L, et al. Among authors: guitart av. Biomolecules. 2021 Apr 10;11(4):558. doi: 10.3390/biom11040558. Biomolecules. 2021. PMID: 33920203 Free PMC article.
Autophagy Targeting and Hematological Mobilization in FLT3-ITD Acute Myeloid Leukemia Decrease Repopulating Capacity and Relapse by Inducing Apoptosis of Committed Leukemic Cells.
Dupont M, Huart M, Lauvinerie C, Bidet A, Guitart AV, Villacreces A, Vigon I, Desplat V, El Habhab A, Pigneux A, Ivanovic Z, Brunet De la Grange P, Dumas PY, Pasquet JM. Dupont M, et al. Among authors: guitart av. Cancers (Basel). 2022 Jan 17;14(2):453. doi: 10.3390/cancers14020453. Cancers (Basel). 2022. PMID: 35053612 Free PMC article.
CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation.
Lawson H, van de Lagemaat LN, Barile M, Tavosanis A, Durko J, Villacreces A, Bellani A, Mapperley C, Georges E, Martins-Costa C, Sepulveda C, Allen L, Campos J, Campbell KJ, O'Carroll D, Göttgens B, Cory S, Rodrigues NP, Guitart AV, Kranc KR. Lawson H, et al. Among authors: guitart av. Stem Cell Reports. 2021 Nov 9;16(11):2784-2797. doi: 10.1016/j.stemcr.2021.10.001. Epub 2021 Oct 28. Stem Cell Reports. 2021. PMID: 34715054 Free PMC article.
Lineage tracing of Pf4-Cre marks hematopoietic stem cells and their progeny.
Calaminus SD, Guitart AV, Sinclair A, Schachtner H, Watson SP, Holyoake TL, Kranc KR, Machesky LM. Calaminus SD, et al. Among authors: guitart av. PLoS One. 2012;7(12):e51361. doi: 10.1371/journal.pone.0051361. Epub 2012 Dec 27. PLoS One. 2012. PMID: 23300543 Free PMC article.
21 results