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A sulphated glycosaminoglycan extract from Placopecten magellanicus inhibits the Alzheimer's disease β-site amyloid precursor protein cleaving enzyme 1 (BACE-1).
Mycroft-West CJ, Devlin AJ, Cooper LC, Guimond SE, Procter P, Miller GJ, Guerrini M, Fernig DG, Yates EA, Lima MA, Skidmore MA. Mycroft-West CJ, et al. Among authors: guimond se. Carbohydr Res. 2023 Mar;525:108747. doi: 10.1016/j.carres.2023.108747. Epub 2023 Jan 26. Carbohydr Res. 2023. PMID: 36773398
Disruption of rosetting in Plasmodium falciparum malaria with chemically modified heparin and low molecular weight derivatives possessing reduced anticoagulant and other serine protease inhibition activities.
Skidmore MA, Dumax-Vorzet AF, Guimond SE, Rudd TR, Edwards EA, Turnbull JE, Craig AG, Yates EA. Skidmore MA, et al. Among authors: guimond se. J Med Chem. 2008 Mar 13;51(5):1453-8. doi: 10.1021/jm701337t. Epub 2008 Feb 9. J Med Chem. 2008. PMID: 18260612
47 results