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Page 1
USP9X mediates an acute adaptive response to MAPK suppression in pancreatic cancer but creates multiple actionable therapeutic vulnerabilities.
Perurena N, Lock R, Davis RA, Raghavan S, Pilla NF, Ng R, Loi P, Guild CJ, Miller AL, Sicinska E, Cleary JM, Rubinson DA, Wolpin BM, Gray NS, Santagata S, Hahn WC, Morton JP, Sansom OJ, Aguirre AJ, Cichowski K. Perurena N, et al. Among authors: guild cj. Cell Rep Med. 2023 Apr 18;4(4):101007. doi: 10.1016/j.xcrm.2023.101007. Epub 2023 Apr 7. Cell Rep Med. 2023. PMID: 37030295 Free PMC article.
A Deregulated HOX Gene Axis Confers an Epigenetic Vulnerability in KRAS-Mutant Lung Cancers.
Guerra SL, Maertens O, Kuzmickas R, De Raedt T, Adeyemi RO, Guild CJ, Guillemette S, Redig AJ, Chambers ES, Xu M, Tiv H, Santagata S, Jänne PA, Elledge SJ, Cichowski K. Guerra SL, et al. Among authors: guild cj. Cancer Cell. 2020 May 11;37(5):705-719.e6. doi: 10.1016/j.ccell.2020.03.004. Epub 2020 Apr 2. Cancer Cell. 2020. PMID: 32243838 Free PMC article.
MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in BRAF-, NRAS-, and NF1-Mutant Melanomas.
Maertens O, Kuzmickas R, Manchester HE, Emerson CE, Gavin AG, Guild CJ, Wong TC, De Raedt T, Bowman-Colin C, Hatchi E, Garraway LA, Flaherty KT, Pathania S, Elledge SJ, Cichowski K. Maertens O, et al. Among authors: guild cj. Cancer Discov. 2019 Apr;9(4):526-545. doi: 10.1158/2159-8290.CD-18-0879. Epub 2019 Feb 1. Cancer Discov. 2019. PMID: 30709805 Free PMC article.
N-(4-Bromo-phen-yl)acetamide: a new polymorph.
Jasinski JP, Guild CJ, Yathirajan HS, Narayana B, Samshuddin S. Jasinski JP, et al. Among authors: guild cj. Acta Crystallogr Sect E Struct Rep Online. 2013 Mar 1;69(Pt 3):o461. doi: 10.1107/S1600536813005448. Epub 2013 Feb 28. Acta Crystallogr Sect E Struct Rep Online. 2013. PMID: 23476627 Free PMC article.
Redetermination of loperamide monohydrate.
Jasinski JP, Guild CJ, Dayananda AS, Yathirajan HS, Ramesha AR. Jasinski JP, et al. Among authors: guild cj. Acta Crystallogr Sect E Struct Rep Online. 2012 Feb 1;68(Pt 2):o539-40. doi: 10.1107/S1600536812003091. Epub 2012 Jan 31. Acta Crystallogr Sect E Struct Rep Online. 2012. PMID: 22347134 Free PMC article.
(1E)-1-(3-Bromo-phen-yl)ethanone 2,4-di-nitro-phenyl-hydrazone.
Jasinski JP, Guild CJ, Chidan Kumar CS, Yathirajan HS, Mayekar AN. Jasinski JP, et al. Among authors: guild cj. Acta Crystallogr Sect E Struct Rep Online. 2010 Oct 20;66(Pt 11):o2832-3. doi: 10.1107/S1600536810037980. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21589019 Free PMC article.
2,3-Dibromo-1,3-bis-(4-fluoro-phen-yl)propan-1-one.
Jasinski JP, Guild CJ, Samshuddin S, Narayana B, Yathirajan HS. Jasinski JP, et al. Among authors: guild cj. Acta Crystallogr Sect E Struct Rep Online. 2010 Jul 14;66(Pt 8):o2018. doi: 10.1107/S1600536810026905. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21588329 Free PMC article.
(E)-3-(4-Meth-oxy-phen-yl)-1-[4-(piperidin-1-yl)phen-yl]prop-2-en-1-one.
Jasinski JP, Guild CJ, Narayana B, Nayak PS, Yathirajan HS. Jasinski JP, et al. Among authors: guild cj. Acta Crystallogr Sect E Struct Rep Online. 2010 Jul 14;66(Pt 8):o1996. doi: 10.1107/S1600536810026218. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21588310 Free PMC article.
3,5-Bis(4-fluoro-phen-yl)-1-phenyl-4,5-dihydro-1H-pyrazole.
Jasinski JP, Guild CJ, Samshuddin S, Narayana B, Yathirajan HS. Jasinski JP, et al. Among authors: guild cj. Acta Crystallogr Sect E Struct Rep Online. 2010 Jul 7;66(Pt 8):o1948-9. doi: 10.1107/S1600536810026036. Acta Crystallogr Sect E Struct Rep Online. 2010. PMID: 21588274 Free PMC article.