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CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury.
Leuillier M, Duflot T, Ménoret S, Messaoudi H, Djerada Z, Groussard D, Denis RGP, Chevalier L, Karoui A, Panthu B, Thiébaut PA, Schmitz-Afonso I, Nobis S, Campart C, Henry T, Sautreuil C, Luquet SH, Beseme O, Féliu C, Peyret H, Nicol L, Henry JP, Renet S, Mulder P, Wan D, Tesson L, Heslan JM, Duché A, Jacques S, Ziegler F, Brunel V, Rautureau GJP, Monteil C, do Rego JL, do Rego JC, Afonso C, Hammock B, Madec AM, Pinet F, Richard V, Anegon I, Guignabert C, Morisseau C, Bellien J. Leuillier M, et al. Among authors: guignabert c. J Adv Res. 2023 Jan;43:163-174. doi: 10.1016/j.jare.2022.03.004. Epub 2022 Mar 12. J Adv Res. 2023. PMID: 36585106 Free PMC article.
Different cardiovascular and pulmonary phenotypes for single- and double-knock-out mice deficient in BMP9 and BMP10.
Bouvard C, Tu L, Rossi M, Desroches-Castan A, Berrebeh N, Helfer E, Roelants C, Liu H, Ouarné M, Chaumontel N, Mallet C, Battail C, Bikfalvi A, Humbert M, Savale L, Daubon T, Perret P, Tillet E, Guignabert C, Bailly S. Bouvard C, et al. Among authors: guignabert c. Cardiovasc Res. 2022 Jun 22;118(7):1805-1820. doi: 10.1093/cvr/cvab187. Cardiovasc Res. 2022. PMID: 34086873 Free PMC article.
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension.
Rol N, de Raaf MA, Sun XQ, Kuiper VP, da Silva Gonçalves Bos D, Happé C, Kurakula K, Dickhoff C, Thuillet R, Tu L, Guignabert C, Schalij I, Lodder K, Pan X, Herrmann FE, van Nieuw Amerongen GP, Koolwijk P, Vonk-Noordegraaf A, de Man FS, Wollin L, Goumans MJ, Szulcek R, Bogaard HJ. Rol N, et al. Among authors: guignabert c. Cardiovasc Res. 2019 Feb 1;115(2):432-439. doi: 10.1093/cvr/cvy186. Cardiovasc Res. 2019. PMID: 30032282
Selective BMP-9 Inhibition Partially Protects Against Experimental Pulmonary Hypertension.
Tu L, Desroches-Castan A, Mallet C, Guyon L, Cumont A, Phan C, Robert F, Thuillet R, Bordenave J, Sekine A, Huertas A, Ritvos O, Savale L, Feige JJ, Humbert M, Bailly S, Guignabert C. Tu L, et al. Among authors: guignabert c. Circ Res. 2019 Mar 15;124(6):846-855. doi: 10.1161/CIRCRESAHA.118.313356. Circ Res. 2019. PMID: 30636542 Free article.
Neutralization of CXCL12 attenuates established pulmonary hypertension in rats.
Bordenave J, Thuillet R, Tu L, Phan C, Cumont A, Marsol C, Huertas A, Savale L, Hibert M, Galzi JL, Bonnet D, Humbert M, Frossard N, Guignabert C. Bordenave J, et al. Among authors: guignabert c. Cardiovasc Res. 2020 Mar 1;116(3):686-697. doi: 10.1093/cvr/cvz153. Cardiovasc Res. 2020. PMID: 31173066
170 results