Guerard N - Search Results

1

KESTREL and KITE: 52-Week Results From Two Phase III Pivotal Trials of Brolucizumab for Diabetic Macular Edema.

Brown DM, Emanuelli A, Bandello F, Barranco JJE, Figueira J, Souied E, Wolf S, Gupta V, Ngah NF, Liew G, Tuli R, Tadayoni R, Dhoot D, Wang L, Bouillaud E, Wang Y, Kovacic L, Guerard N, Garweg JG. Brown DM, et al. Among authors: guerard n. Am J Ophthalmol. 2022 Jun;238:157-172. doi: 10.1016/j.ajo.2022.01.004. Epub 2022 Jan 14. Am J Ophthalmol. 2022. PMID: 35038415 Free article. Clinical Trial.

2

Evaluation of cardiac parameters and other safety outcomes of brolucizumab treatment in patients with neovascular age-related macular degeneration.

Zakaria N, Guerard N, Emanuelli A, Dugel P, Watts J, Liew M, Gekkieva M, Hinder M. Zakaria N, et al. Among authors: guerard n. Pharmacol Res Perspect. 2022 Apr;10(2):e00897. doi: 10.1002/prp2.897. Pharmacol Res Perspect. 2022. PMID: 35301822 Free PMC article. Clinical Trial.

3

Lucerastat, an Iminosugar for Substrate Reduction Therapy: Pharmacokinetics, Tolerability, and Safety in Subjects With Mild, Moderate, and Severe Renal Function Impairment.

Guérard N, Zwingelstein C, Dingemanse J. Guérard N, et al. J Clin Pharmacol. 2017 Nov;57(11):1425-1431. doi: 10.1002/jcph.944. Epub 2017 Jun 15. J Clin Pharmacol. 2017. PMID: 28618006 Clinical Trial.

4

Effect of Hepatic or Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of Ponesimod, a Selective S1P1 Receptor Modulator.

Guérard N, Zwingelstein C, Hoch M, Dingemanse J. Guérard N, et al. Basic Clin Pharmacol Toxicol. 2016 May;118(5):356-68. doi: 10.1111/bcpt.12516. Epub 2015 Dec 10. Basic Clin Pharmacol Toxicol. 2016. PMID: 26525450 Free article. Clinical Trial.

5

Effects of the Dual Endothelin Receptor Antagonist Aprocitentan on Body Weight and Fluid Homeostasis in Healthy Subjects on a High Sodium Diet.

Gueneau de Mussy P, Sidharta PN, Wuerzner G, Maillard MP, Guérard N, Iglarz M, Flamion B, Dingemanse J, Burnier M. Gueneau de Mussy P, et al. Among authors: guerard n. Clin Pharmacol Ther. 2021 Mar;109(3):746-753. doi: 10.1002/cpt.2043. Epub 2020 Sep 29. Clin Pharmacol Ther. 2021. PMID: 32897570 Free PMC article. Clinical Trial.

6

Lucerastat, an iminosugar with potential as substrate reduction therapy for glycolipid storage disorders: safety, tolerability, and pharmacokinetics in healthy subjects.

Guérard N, Morand O, Dingemanse J. Guérard N, et al. Orphanet J Rare Dis. 2017 Jan 14;12(1):9. doi: 10.1186/s13023-017-0565-9. Orphanet J Rare Dis. 2017. PMID: 28088251 Free PMC article. Clinical Trial.

7

Lucerastat, an Iminosugar for Substrate Reduction Therapy: Tolerability, Pharmacodynamics, and Pharmacokinetics in Patients With Fabry Disease on Enzyme Replacement.

Guérard N, Oder D, Nordbeck P, Zwingelstein C, Morand O, Welford RWD, Dingemanse J, Wanner C. Guérard N, et al. Clin Pharmacol Ther. 2018 Apr;103(4):703-711. doi: 10.1002/cpt.790. Epub 2017 Aug 28. Clin Pharmacol Ther. 2018. PMID: 28699267 Clinical Trial.

8

Selective block of IKs plays a significant role in MAP triangulation induced by IKr block in isolated rabbit heart.

Guérard NC, Traebert M, Suter W, Dumotier BM. Guérard NC, et al. J Pharmacol Toxicol Methods. 2008 Jul-Aug;58(1):32-40. doi: 10.1016/j.vascn.2008.05.129. Epub 2008 Jun 8. J Pharmacol Toxicol Methods. 2008. PMID: 18582585

9

Analysis of unipolar electrograms in rabbit heart demonstrated the key role of ventricular apicobasal dispersion in arrhythmogenicity.

Guérard N, Jordaan P, Dumotier B. Guérard N, et al. Cardiovasc Toxicol. 2014 Dec;14(4):316-28. doi: 10.1007/s12012-014-9254-2. Cardiovasc Toxicol. 2014. PMID: 24740433

10

Analysing branching pattern in plantations of young red oak trees (Quercus rubra L., Fagaceae).

Heuret P, Guédon Y, Guérard N, Barthélémy D. Heuret P, et al. Among authors: guerard n. Ann Bot. 2003 Mar;91(4):479-92. doi: 10.1093/aob/mcg046. Ann Bot. 2003. PMID: 12588728 Free PMC article.

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