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308 results

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A lung/liver-on-a-chip platform for acute and chronic toxicity studies.
Bovard D, Sandoz A, Luettich K, Frentzel S, Iskandar A, Marescotti D, Trivedi K, Guedj E, Dutertre Q, Peitsch MC, Hoeng J. Bovard D, et al. Among authors: guedj e. Lab Chip. 2018 Dec 4;18(24):3814-3829. doi: 10.1039/c8lc01029c. Lab Chip. 2018. PMID: 30460365
A 7-month cigarette smoke inhalation study in C57BL/6 mice demonstrates reduced lung inflammation and emphysema following smoking cessation or aerosol exposure from a prototypic modified risk tobacco product.
Phillips B, Veljkovic E, Peck MJ, Buettner A, Elamin A, Guedj E, Vuillaume G, Ivanov NV, Martin F, Boué S, Schlage WK, Schneider T, Titz B, Talikka M, Vanscheeuwijck P, Hoeng J, Peitsch MC. Phillips B, et al. Among authors: guedj e. Food Chem Toxicol. 2015 Jun;80:328-345. doi: 10.1016/j.fct.2015.03.009. Epub 2015 Apr 2. Food Chem Toxicol. 2015. PMID: 25843363 Free article.
Transcriptional profiling and targeted proteomics reveals common molecular changes associated with cigarette smoke-induced lung emphysema development in five susceptible mouse strains.
Cabanski M, Fields B, Boue S, Boukharov N, DeLeon H, Dror N, Geertz M, Guedj E, Iskandar A, Kogel U, Merg C, Peck MJ, Poussin C, Schlage WK, Talikka M, Ivanov NV, Hoeng J, Peitsch MC. Cabanski M, et al. Among authors: guedj e. Inflamm Res. 2015 Jul;64(7):471-86. doi: 10.1007/s00011-015-0820-2. Epub 2015 May 12. Inflamm Res. 2015. PMID: 25962837 Free PMC article.
Impact Assessment of Cigarette Smoke Exposure on Organotypic Bronchial Epithelial Tissue Cultures: A Comparison of Mono-Culture and Coculture Model Containing Fibroblasts.
Iskandar AR, Xiang Y, Frentzel S, Talikka M, Leroy P, Kuehn D, Guedj E, Martin F, Mathis C, Ivanov NV, Peitsch MC, Hoeng J. Iskandar AR, et al. Among authors: guedj e. Toxicol Sci. 2015 Sep;147(1):207-21. doi: 10.1093/toxsci/kfv122. Epub 2015 Jun 16. Toxicol Sci. 2015. PMID: 26085348 Free PMC article.
Alterations in the sputum proteome and transcriptome in smokers and early-stage COPD subjects.
Titz B, Sewer A, Schneider T, Elamin A, Martin F, Dijon S, Luettich K, Guedj E, Vuillaume G, Ivanov NV, Peck MJ, Chaudhary NI, Hoeng J, Peitsch MC. Titz B, et al. Among authors: guedj e. J Proteomics. 2015 Oct 14;128:306-20. doi: 10.1016/j.jprot.2015.08.009. Epub 2015 Aug 22. J Proteomics. 2015. PMID: 26306861 Free article. Clinical Trial.
Effects of Cigarette Smoke, Cessation, and Switching to Two Heat-Not-Burn Tobacco Products on Lung Lipid Metabolism in C57BL/6 and Apoe-/- Mice-An Integrative Systems Toxicology Analysis.
Titz B, Boué S, Phillips B, Talikka M, Vihervaara T, Schneider T, Nury C, Elamin A, Guedj E, Peck MJ, Schlage WK, Cabanski M, Leroy P, Vuillaume G, Martin F, Ivanov NV, Veljkovic E, Ekroos K, Laaksonen R, Vanscheeuwijck P, Peitsch MC, Hoeng J. Titz B, et al. Among authors: guedj e. Toxicol Sci. 2016 Feb;149(2):441-57. doi: 10.1093/toxsci/kfv244. Epub 2015 Nov 17. Toxicol Sci. 2016. PMID: 26582801 Free PMC article.
An 8-Month Systems Toxicology Inhalation/Cessation Study in Apoe-/- Mice to Investigate Cardiovascular and Respiratory Exposure Effects of a Candidate Modified Risk Tobacco Product, THS 2.2, Compared With Conventional Cigarettes.
Phillips B, Veljkovic E, Boué S, Schlage WK, Vuillaume G, Martin F, Titz B, Leroy P, Buettner A, Elamin A, Oviedo A, Cabanski M, De León H, Guedj E, Schneider T, Talikka M, Ivanov NV, Vanscheeuwijck P, Peitsch MC, Hoeng J. Phillips B, et al. Among authors: guedj e. Toxicol Sci. 2016 Feb;149(2):411-32. doi: 10.1093/toxsci/kfv243. Epub 2015 Nov 25. Toxicol Sci. 2016. PMID: 26609137 Free PMC article.
In Vitro Systems Toxicology Assessment of a Candidate Modified Risk Tobacco Product Shows Reduced Toxicity Compared to That of a Conventional Cigarette.
Gonzalez-Suarez I, Martin F, Marescotti D, Guedj E, Acali S, Johne S, Dulize R, Baumer K, Peric D, Goedertier D, Frentzel S, Ivanov NV, Mathis C, Hoeng J, Peitsch MC. Gonzalez-Suarez I, et al. Among authors: guedj e. Chem Res Toxicol. 2016 Jan 19;29(1):3-18. doi: 10.1021/acs.chemrestox.5b00321. Epub 2015 Dec 29. Chem Res Toxicol. 2016. PMID: 26651182
308 results