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Context-Dependent Effects of Amplified MAPK Signaling during Lung Adenocarcinoma Initiation and Progression.
Cell Rep. 2017 Feb 21;18(8):1958-1969. doi: 10.1016/j.celrep.2017.01.069.
Cell Rep. 2017.
PMID: 28228261
Free PMC article.
Copper is an essential regulator of the autophagic kinases ULK1/2 to drive lung adenocarcinoma.
Tsang T, Posimo JM, Gudiel AA, Cicchini M, Feldser DM, Brady DC.
Tsang T, et al. Among authors: gudiel aa.
Nat Cell Biol. 2020 Apr;22(4):412-424. doi: 10.1038/s41556-020-0481-4. Epub 2020 Mar 16.
Nat Cell Biol. 2020.
PMID: 32203415
Free PMC article.
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Systematic In Vivo Inactivation of Chromatin-Regulating Enzymes Identifies Setd2 as a Potent Tumor Suppressor in Lung Adenocarcinoma.
Walter DM, Venancio OS, Buza EL, Tobias JW, Deshpande C, Gudiel AA, Kim-Kiselak C, Cicchini M, Yates TJ, Feldser DM.
Walter DM, et al. Among authors: gudiel aa.
Cancer Res. 2017 Apr 1;77(7):1719-1729. doi: 10.1158/0008-5472.CAN-16-2159. Epub 2017 Feb 15.
Cancer Res. 2017.
PMID: 28202515
Free PMC article.
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RB constrains lineage fidelity and multiple stages of tumour progression and metastasis.
Walter DM, Yates TJ, Ruiz-Torres M, Kim-Kiselak C, Gudiel AA, Deshpande C, Wang WZ, Cicchini M, Stokes KL, Tobias JW, Buza E, Feldser DM.
Walter DM, et al. Among authors: gudiel aa.
Nature. 2019 May;569(7756):423-427. doi: 10.1038/s41586-019-1172-9. Epub 2019 May 1.
Nature. 2019.
PMID: 31043741
Free PMC article.
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Blocking EGFR palmitoylation suppresses PI3K signaling and mutant KRAS lung tumorigenesis.
Kharbanda A, Walter DM, Gudiel AA, Schek N, Feldser DM, Witze ES.
Kharbanda A, et al. Among authors: gudiel aa.
Sci Signal. 2020 Mar 3;13(621):eaax2364. doi: 10.1126/scisignal.aax2364.
Sci Signal. 2020.
PMID: 32127496
Free PMC article.
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Setd2 inactivation sensitizes lung adenocarcinoma to inhibitors of oxidative respiration and mTORC1 signaling.
Walter DM, Gladstein AC, Doerig KR, Natesan R, Baskaran SG, Gudiel AA, Adler KM, Acosta JO, Wallace DC, Asangani IA, Feldser DM.
Walter DM, et al. Among authors: gudiel aa.
Commun Biol. 2023 Mar 10;6(1):255. doi: 10.1038/s42003-023-04618-3.
Commun Biol. 2023.
PMID: 36899051
Free PMC article.
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