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SIRT1 promotes differentiation of normal human keratinocytes.
Blander G, Bhimavarapu A, Mammone T, Maes D, Elliston K, Reich C, Matsui MS, Guarente L, Loureiro JJ. Blander G, et al. Among authors: guarente l. J Invest Dermatol. 2009 Jan;129(1):41-9. doi: 10.1038/jid.2008.179. Epub 2008 Jun 19. J Invest Dermatol. 2009. PMID: 18563176 Free PMC article.
The Sir2 family of protein deacetylases.
Blander G, Guarente L. Blander G, et al. Among authors: guarente l. Annu Rev Biochem. 2004;73:417-35. doi: 10.1146/annurev.biochem.73.011303.073651. Annu Rev Biochem. 2004. PMID: 15189148 Review.
SIRT1 shows no substrate specificity in vitro.
Blander G, Olejnik J, Krzymanska-Olejnik E, McDonagh T, Haigis M, Yaffe MB, Guarente L. Blander G, et al. Among authors: guarente l. J Biol Chem. 2005 Mar 18;280(11):9780-5. doi: 10.1074/jbc.M414080200. Epub 2005 Jan 6. J Biol Chem. 2005. PMID: 15640142 Free article.
Neurogenesis directed by Sirt1.
Libert S, Cohen D, Guarente L. Libert S, et al. Among authors: guarente l. Nat Cell Biol. 2008 Apr;10(4):373-4. doi: 10.1038/ncb0408-373. Nat Cell Biol. 2008. PMID: 18379594 Free PMC article.
Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma.
Picard F, Kurtev M, Chung N, Topark-Ngarm A, Senawong T, Machado De Oliveira R, Leid M, McBurney MW, Guarente L. Picard F, et al. Among authors: guarente l. Nature. 2004 Jun 17;429(6993):771-6. doi: 10.1038/nature02583. Epub 2004 Jun 2. Nature. 2004. PMID: 15175761 Free PMC article.
Mammalian SIRT1 represses forkhead transcription factors.
Motta MC, Divecha N, Lemieux M, Kamel C, Chen D, Gu W, Bultsma Y, McBurney M, Guarente L. Motta MC, et al. Among authors: guarente l. Cell. 2004 Feb 20;116(4):551-63. doi: 10.1016/s0092-8674(04)00126-6. Cell. 2004. PMID: 14980222 Free article.
302 results