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751 results

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PBRM1-deficient PBAF complexes target aberrant genomic loci to activate the NF-κB pathway in clear cell renal cell carcinoma.
Yao X, Hong JH, Nargund AM, Ng MSW, Heng HL, Li Z, Guan P, Sugiura M, Chu PL, Wang LC, Ye X, Qu J, Kwek XY, Lim JCT, Ooi WF, Koh J, Wang Z, Pan YF, Ong YS, Tan KY, Goh JY, Ng SR, Pignata L, Huang D, Lezhava A, Tay ST, Lee M, Yeo XH, Tam WL, Rha SY, Li S, Guccione E, Futreal A, Tan J, Yeong JPS, Hong W, Yauch R, Chang KT, Sobota RM, Tan P, Teh BT. Yao X, et al. Among authors: guan p. Nat Cell Biol. 2023 May;25(5):765-777. doi: 10.1038/s41556-023-01122-y. Epub 2023 Apr 24. Nat Cell Biol. 2023. PMID: 37095322
Genome-wide mutational signatures of aristolochic acid and its application as a screening tool.
Poon SL, Pang ST, McPherson JR, Yu W, Huang KK, Guan P, Weng WH, Siew EY, Liu Y, Heng HL, Chong SC, Gan A, Tay ST, Lim WK, Cutcutache I, Huang D, Ler LD, Nairismägi ML, Lee MH, Chang YH, Yu KJ, Chan-On W, Li BK, Yuan YF, Qian CN, Ng KF, Wu CF, Hsu CL, Bunte RM, Stratton MR, Futreal PA, Sung WK, Chuang CK, Ong CK, Rozen SG, Tan P, Teh BT. Poon SL, et al. Among authors: guan p. Sci Transl Med. 2013 Aug 7;5(197):197ra101. doi: 10.1126/scitranslmed.3006086. Sci Transl Med. 2013. PMID: 23926199
VHL Deficiency Drives Enhancer Activation of Oncogenes in Clear Cell Renal Cell Carcinoma.
Yao X, Tan J, Lim KJ, Koh J, Ooi WF, Li Z, Huang D, Xing M, Chan YS, Qu JZ, Tay ST, Wijaya G, Lam YN, Hong JH, Lee-Lim AP, Guan P, Ng MSW, He CZ, Lin JS, Nandi T, Qamra A, Xu C, Myint SS, Davies JOJ, Goh JY, Loh G, Tan BC, Rozen SG, Yu Q, Tan IBH, Cheng CWS, Li S, Chang KTE, Tan PH, Silver DL, Lezhava A, Steger G, Hughes JR, Teh BT, Tan P. Yao X, et al. Among authors: guan p. Cancer Discov. 2017 Nov;7(11):1284-1305. doi: 10.1158/2159-8290.CD-17-0375. Epub 2017 Sep 11. Cancer Discov. 2017. PMID: 28893800
Molecular insights into paediatric breast fibroepithelial tumours.
Tay TKY, Guan P, Loke BN, Nasir NDM, Rajasegaran V, Thike AA, Lian D, Chang KTE, Teh BT, Ng CCY, Tan PH. Tay TKY, et al. Among authors: guan p. Histopathology. 2018 Nov;73(5):809-818. doi: 10.1111/his.13701. Epub 2018 Aug 22. Histopathology. 2018. PMID: 29969836
Genomic profile of breast sarcomas: a comparison with malignant phyllodes tumours.
Lim SZ, Ng CCY, Rajasegaran V, Guan P, Selvarajan S, Thike AA, Nasir NDBM, Koh VCY, Tan BKT, Ong KW, Teh BT, Tan PH. Lim SZ, et al. Among authors: guan p. Breast Cancer Res Treat. 2019 Apr;174(2):365-373. doi: 10.1007/s10549-018-5067-5. Epub 2018 Dec 3. Breast Cancer Res Treat. 2019. PMID: 30511242
Genomic characterisation of breast fibroepithelial lesions in an international cohort.
Md Nasir ND, Ng CCY, Rajasegaran V, Wong SF, Liu W, Ng GXP, Lee JY, Guan P, Lim JQ, Thike AA, Koh VCY, Loke BN, Chang KTE, Gudi MA, Lian DWQ, Madhukumar P, Tan BKT, Tan VKM, Wong CY, Yong WS, Ho GH, Ong KW; International Fibroepithelial Consortium; Tan P, Teh BT, Tan PH. Md Nasir ND, et al. Among authors: guan p. J Pathol. 2019 Dec;249(4):447-460. doi: 10.1002/path.5333. Epub 2019 Oct 8. J Pathol. 2019. PMID: 31411343
A novel genomic panel as an adjunctive diagnostic tool for the characterization and profiling of breast Fibroepithelial lesions.
Sim Y, Ng GXP, Ng CCY, Rajasegaran V, Wong SF, Liu W, Guan P, Nagarajan S, Ng WY, Thike AA, Lim JCT, Nasir NDBM, Tan VKM, Madhukumar P, Yong WS, Wong CY, Tan BKT, Ong KW, Teh BT, Tan PH. Sim Y, et al. Among authors: guan p. BMC Med Genomics. 2019 Oct 23;12(1):142. doi: 10.1186/s12920-019-0588-2. BMC Med Genomics. 2019. PMID: 31647027 Free PMC article.
MED12, TERT and RARA in fibroepithelial tumours of the breast.
Chang HY, Koh VCY, Md Nasir ND, Ng CCY, Guan P, Thike AA, Teh BT, Tan PH. Chang HY, et al. Among authors: guan p. J Clin Pathol. 2020 Jan;73(1):51-56. doi: 10.1136/jclinpath-2019-206208. Epub 2019 Oct 29. J Clin Pathol. 2020. PMID: 31662438 Review.
751 results