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TEAD mediates YAP-dependent gene induction and growth control.
Zhao B, Ye X, Yu J, Li L, Li W, Li S, Yu J, Lin JD, Wang CY, Chinnaiyan AM, Lai ZC, Guan KL. Zhao B, et al. Among authors: guan kl. Genes Dev. 2008 Jul 15;22(14):1962-71. doi: 10.1101/gad.1664408. Epub 2008 Jun 25. Genes Dev. 2008. PMID: 18579750 Free PMC article.
Regulation of TORC1 by Rag GTPases in nutrient response.
Kim E, Goraksha-Hicks P, Li L, Neufeld TP, Guan KL. Kim E, et al. Among authors: guan kl. Nat Cell Biol. 2008 Aug;10(8):935-45. doi: 10.1038/ncb1753. Epub 2008 Jul 6. Nat Cell Biol. 2008. PMID: 18604198 Free PMC article.
Critical roles for the TSC-mTOR pathway in β-cell function.
Mori H, Inoki K, Opland D, Münzberg H, Villanueva EC, Faouzi M, Ikenoue T, Kwiatkowski DJ, Macdougald OA, Myers MG Jr, Guan KL. Mori H, et al. Among authors: guan kl. Am J Physiol Endocrinol Metab. 2009 Nov;297(5):E1013-22. doi: 10.1152/ajpendo.00262.2009. Epub 2009 Aug 18. Am J Physiol Endocrinol Metab. 2009. PMID: 19690069 Free PMC article.
Regulation of mTORC1 by the Rab and Arf GTPases.
Li L, Kim E, Yuan H, Inoki K, Goraksha-Hicks P, Schiesher RL, Neufeld TP, Guan KL. Li L, et al. Among authors: guan kl. J Biol Chem. 2010 Jun 25;285(26):19705-9. doi: 10.1074/jbc.C110.102483. Epub 2010 May 10. J Biol Chem. 2010. PMID: 20457610 Free PMC article.
MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice.
Zhang D, Contu R, Latronico MV, Zhang J, Rizzi R, Catalucci D, Miyamoto S, Huang K, Ceci M, Gu Y, Dalton ND, Peterson KL, Guan KL, Brown JH, Chen J, Sonenberg N, Condorelli G. Zhang D, et al. Among authors: guan kl. J Clin Invest. 2010 Aug;120(8):2805-16. doi: 10.1172/JCI43008. Epub 2010 Jul 19. J Clin Invest. 2010. PMID: 20644257 Free PMC article.
441 results