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LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition.
Proteau S, Krossa I, Husser C, Guéguinou M, Sella F, Bille K, Irondelle M, Dalmasso M, Barouillet T, Cheli Y, Pisibon C, Arrighi N, Nahon-Estève S, Martel A, Gastaud L, Lassalle S, Mignen O, Brest P, Mazure NM, Bost F, Baillif S, Landreville S, Turcotte S, Hasson D, Carcamo S, Vandier C, Bernstein E, Yvan-Charvet L, Levesque MP, Ballotti R, Bertolotto C, Strub T. Proteau S, et al. Among authors: gueguinou m. EMBO Mol Med. 2023 Dec 7;15(12):e17719. doi: 10.15252/emmm.202317719. Epub 2023 Nov 15. EMBO Mol Med. 2023. PMID: 37966164 Free PMC article.
Potassium and Calcium Channel Complexes as Novel Targets for Cancer Research.
Potier-Cartereau M, Raoul W, Weber G, Mahéo K, Rapetti-Mauss R, Gueguinou M, Buscaglia P, Goupille C, Le Goux N, Abdoul-Azize S, Lecomte T, Fromont G, Chantome A, Mignen O, Soriani O, Vandier C. Potier-Cartereau M, et al. Among authors: gueguinou m. Rev Physiol Biochem Pharmacol. 2022;183:157-176. doi: 10.1007/112_2020_24. Rev Physiol Biochem Pharmacol. 2022. PMID: 32767122
SK3/TRPC1/Orai1 complex regulates SOCE-dependent colon cancer cell migration: a novel opportunity to modulate anti-EGFR mAb action by the alkyl-lipid Ohmline.
Guéguinou M, Harnois T, Crottes D, Uguen A, Deliot N, Gambade A, Chantôme A, Haelters JP, Jaffrès PA, Jourdan ML, Weber G, Soriani O, Bougnoux P, Mignen O, Bourmeyster N, Constantin B, Lecomte T, Vandier C, Potier-Cartereau M. Guéguinou M, et al. Oncotarget. 2016 Jun 14;7(24):36168-36184. doi: 10.18632/oncotarget.8786. Oncotarget. 2016. PMID: 27102434 Free PMC article.
The SigmaR1 chaperone drives breast and colorectal cancer cell migration by tuning SK3-dependent Ca2+ homeostasis.
Gueguinou M, Crottès D, Chantôme A, Rapetti-Mauss R, Potier-Cartereau M, Clarysse L, Girault A, Fourbon Y, Jézéquel P, Guérin-Charbonnel C, Fromont G, Martin P, Pellissier B, Schiappa R, Chamorey E, Mignen O, Uguen A, Borgese F, Vandier C, Soriani O. Gueguinou M, et al. Oncogene. 2017 Jun 22;36(25):3640-3647. doi: 10.1038/onc.2016.501. Epub 2017 Jan 23. Oncogene. 2017. PMID: 28114279
Ca2+ protein alpha 1D of CaV1.3 regulates intracellular calcium concentration and migration of colon cancer cells through a non-canonical activity.
Fourbon Y, Guéguinou M, Félix R, Constantin B, Uguen A, Fromont G, Lajoie L, Magaud C, Lecomte T, Chamorey E, Chatelier A, Mignen O, Potier-Cartereau M, Chantôme A, Bois P, Vandier C. Fourbon Y, et al. Among authors: gueguinou m. Sci Rep. 2017 Oct 27;7(1):14199. doi: 10.1038/s41598-017-14230-1. Sci Rep. 2017. PMID: 29079724 Free PMC article.
SKCa- and Kv1-type potassium channels and cancer: Promising therapeutic targets?
Dupuy M, Gueguinou M, Potier-Cartereau M, Lézot F, Papin M, Chantôme A, Rédini F, Vandier C, Verrecchia F. Dupuy M, et al. Among authors: gueguinou m. Biochem Pharmacol. 2023 Oct;216:115774. doi: 10.1016/j.bcp.2023.115774. Epub 2023 Sep 5. Biochem Pharmacol. 2023. PMID: 37678626 Free article. Review.
37 results