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Circulating cell-free DNA in health and disease - the relationship to health behaviours, ageing phenotypes and metabolomics.
Kananen L, Hurme M, Bürkle A, Moreno-Villanueva M, Bernhardt J, Debacq-Chainiaux F, Grubeck-Loebenstein B, Malavolta M, Basso A, Piacenza F, Collino S, Gonos ES, Sikora E, Gradinaru D, Jansen EHJM, Dollé MET, Salmon M, Stuetz W, Weber D, Grune T, Breusing N, Simm A, Capri M, Franceschi C, Slagboom E, Talbot D, Libert C, Raitanen J, Koskinen S, Härkänen T, Stenholm S, Ala-Korpela M, Lehtimäki T, Raitakari OT, Ukkola O, Kähönen M, Jylhä M, Jylhävä J. Kananen L, et al. Among authors: grubeck loebenstein b. Geroscience. 2023 Feb;45(1):85-103. doi: 10.1007/s11357-022-00590-8. Epub 2022 Jul 21. Geroscience. 2023. PMID: 35864375 Free PMC article.
Ageing affects subtelomeric DNA methylation in blood cells from a large European population enrolled in the MARK-AGE study.
Bacalini MG, Reale A, Malavolta M, Ciccarone F, Moreno-Villanueva M, Dollé MET, Jansen E, Grune T, Gonos ES, Schön C, Bernhardt J, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Capri M, Hervonen A, Hurme M, Slagboom PE, Breusing N, Aversano V, Tagliatesta S, Franceschi C, Blasco MA, Bürkle A, Caiafa P, Zampieri M. Bacalini MG, et al. Among authors: grubeck loebenstein b. Geroscience. 2021 Jun;43(3):1283-1302. doi: 10.1007/s11357-021-00347-9. Epub 2021 Apr 19. Geroscience. 2021. PMID: 33870444 Free PMC article.
Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains.
Kananen L, Enroth L, Raitanen J, Jylhävä J, Bürkle A, Moreno-Villanueva M, Bernhardt J, Toussaint O, Grubeck-Loebenstein B, Malavolta M, Basso A, Piacenza F, Collino S, Gonos ES, Sikora E, Gradinaru D, Jansen EHJM, Dollé MET, Salmon M, Stuetz W, Weber D, Grune T, Breusing N, Simm A, Capri M, Franceschi C, Slagboom PE, Talbot DCS, Libert C, Koskinen S, Bruunsgaard H, Hansen ÅM, Lund R, Hurme M, Jylhä M. Kananen L, et al. Among authors: grubeck loebenstein b. Sci Rep. 2021 Mar 17;11(1):6139. doi: 10.1038/s41598-021-85668-7. Sci Rep. 2021. PMID: 33731775 Free PMC article.
MARK-AGE biomarkers of ageing.
Bürkle A, Moreno-Villanueva M, Bernhard J, Blasco M, Zondag G, Hoeijmakers JH, Toussaint O, Grubeck-Loebenstein B, Mocchegiani E, Collino S, Gonos ES, Sikora E, Gradinaru D, Dollé M, Salmon M, Kristensen P, Griffiths HR, Libert C, Grune T, Breusing N, Simm A, Franceschi C, Capri M, Talbot D, Caiafa P, Friguet B, Slagboom PE, Hervonen A, Hurme M, Aspinall R. Bürkle A, et al. Mech Ageing Dev. 2015 Nov;151:2-12. doi: 10.1016/j.mad.2015.03.006. Epub 2015 Mar 24. Mech Ageing Dev. 2015. PMID: 25818235 Free article. Review.
Age-dependent expression of DNMT1 and DNMT3B in PBMCs from a large European population enrolled in the MARK-AGE study.
Ciccarone F, Malavolta M, Calabrese R, Guastafierro T, Bacalini MG, Reale A, Franceschi C, Capri M, Hervonen A, Hurme M, Grubeck-Loebenstein B, Koller B, Bernhardt J, Schӧn C, Slagboom PE, Toussaint O, Sikora E, Gonos ES, Breusing N, Grune T, Jansen E, Dollé M, Moreno-Villanueva M, Sindlinger T, Bürkle A, Zampieri M, Caiafa P. Ciccarone F, et al. Aging Cell. 2016 Aug;15(4):755-65. doi: 10.1111/acel.12485. Epub 2016 May 11. Aging Cell. 2016. PMID: 27169697 Free PMC article.
Zinc-Induced Metallothionein in Centenarian Offspring From a Large European Population: The MARK-AGE Project.
Giacconi R, Costarelli L, Piacenza F, Basso A, Bürkle A, Moreno-Villanueva M, Grune T, Weber D, Stuetz W, Gonos ES, Schön C, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Franceschi C, Hervonen A, Slagboom E, Ciccarone F, Zampieri M, Caiafa P, Jansen E, Dollé MET, Breusing N, Mocchegiani E, Malavolta M. Giacconi R, et al. J Gerontol A Biol Sci Med Sci. 2018 May 9;73(6):745-753. doi: 10.1093/gerona/glx192. J Gerontol A Biol Sci Med Sci. 2018. PMID: 29045571
Antioxidants linked with physical, cognitive and psychological frailty: Analysis of candidate biomarkers and markers derived from the MARK-AGE study.
Rietman ML, Spijkerman AMW, Wong A, van Steeg H, Bürkle A, Moreno-Villanueva M, Sindlinger T, Franceschi C, Grubeck-Loebenstein B, Bernhardt J, Slagboom PE, Toussaint O, Debacq-Chainiaux F, Sikora E, Gonos ES, Breusing N, Stuetz W, Weber D, Grune T, Basso A, Piacenza F, Malavolta M, Collino S, Jansen EHJM, Verschuren WMM, Dollé MET. Rietman ML, et al. Mech Ageing Dev. 2019 Jan;177:135-143. doi: 10.1016/j.mad.2018.04.007. Epub 2018 Apr 30. Mech Ageing Dev. 2019. PMID: 29719199 Clinical Trial.
Prevalence and Loads of Torquetenovirus in the European MARK-AGE Study Population.
Giacconi R, Maggi F, Macera L, Spezia PG, Pistello M, Provinciali M, Piacenza F, Basso A, Bürkle A, Moreno-Villanueva M, Dollé MET, Jansen E, Grune T, Stuetz W, Gonos ES, Schön C, Bernhardt J, Grubeck-Loebenstein B, Sikora E, Dudkowska M, Janiszewska D, Toussaint O, Debacq-Chainiaux F, Franceschi C, Capri M, Hervonen A, Hurme M, Slagboom E, Breusing N, Mocchegiani E, Malavolta M. Giacconi R, et al. J Gerontol A Biol Sci Med Sci. 2020 Sep 25;75(10):1838-1845. doi: 10.1093/gerona/glz293. J Gerontol A Biol Sci Med Sci. 2020. PMID: 31838498
Medication Intake Is Associated with Lower Plasma Carotenoids and Higher Fat-Soluble Vitamins in the Cross-Sectional MARK-AGE Study in Older Individuals.
Weber D, Kochlik B, Stuetz W, Dollé MET, Jansen EHJM, Grubeck-Loebenstein B, Debacq-Chainiaux F, Bernhardt J, Gonos ES, Capri M, Franceschi C, Sikora E, Moreno-Villanueva M, Bürkle A, Grune T. Weber D, et al. J Clin Med. 2020 Jul 1;9(7):2072. doi: 10.3390/jcm9072072. J Clin Med. 2020. PMID: 32630295 Free PMC article.
Age, Sex, and BMI Influence on Copper, Zinc, and Their Major Serum Carrier Proteins in a Large European Population Including Nonagenarian Offspring From MARK-AGE Study.
Piacenza F, Giacconi R, Costarelli L, Basso A, Bürkle A, Moreno-Villanueva M, Dollé MET, Jansen E, Grune T, Weber D, Stuetz W, Gonos ES, Schön C, Bernhardt J, Grubeck-Loebenstein B, Sikora E, Toussaint O, Debacq-Chainiaux F, Franceschi C, Capri M, Hervonen A, Hurme M, Slagboom E, Breusing N, Mocchegiani E, Malavolta M. Piacenza F, et al. Among authors: grubeck loebenstein b. J Gerontol A Biol Sci Med Sci. 2021 Nov 15;76(12):2097-2106. doi: 10.1093/gerona/glab134. J Gerontol A Biol Sci Med Sci. 2021. PMID: 33983441
238 results