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An Update on JAK Inhibitors.
Musumeci F, Greco C, Giacchello I, Fallacara AL, Ibrahim MM, Grossi G, Brullo C, Schenone S. Musumeci F, et al. Among authors: grossi g. Curr Med Chem. 2019;26(10):1806-1832. doi: 10.2174/0929867325666180327093502. Curr Med Chem. 2019. PMID: 29589523 Review.
Synthesis and in vitro antiplatelet activity of new 4-(1-piperazinyl)coumarin derivatives. Human platelet phosphodiesterase 3 inhibitory properties of the two most effective compounds described and molecular modeling study on their interactions with phosphodiesterase 3A catalytic site.
Roma G, Di Braccio M, Grossi G, Piras D, Leoncini G, Bruzzese D, Signorello MG, Fossa P, Mosti L. Roma G, et al. Among authors: grossi g. J Med Chem. 2007 Jun 14;50(12):2886-95. doi: 10.1021/jm0611511. Epub 2007 May 15. J Med Chem. 2007. PMID: 17500510
1,8-Naphthyridines VII. New substituted 5-amino[1,2,4]triazolo[4,3-a][1,8]naphthyridine-6-carboxamides and their isosteric analogues, exhibiting notable anti-inflammatory and/or analgesic activities, but no acute gastrolesivity.
Roma G, Grossi G, Di Braccio M, Piras D, Ballabeni V, Tognolini M, Bertoni S, Barocelli E. Roma G, et al. Among authors: grossi g. Eur J Med Chem. 2008 Aug;43(8):1665-80. doi: 10.1016/j.ejmech.2007.10.010. Epub 2007 Oct 11. Eur J Med Chem. 2008. PMID: 18045747
1,8-Naphthyridines VIII. Novel 5-aminoimidazo[1,2-a] [1,8]naphthyridine-6-carboxamide and 5-amino[1,2,4]triazolo[4,3-a] [1,8]naphthyridine-6-carboxamide derivatives showing potent analgesic or anti-inflammatory activity, respectively, and completely devoid of acute gastrolesivity.
Roma G, Di Braccio M, Grossi G, Piras D, Ballabeni V, Tognolini M, Bertoni S, Barocelli E. Roma G, et al. Among authors: grossi g. Eur J Med Chem. 2010 Jan;45(1):352-66. doi: 10.1016/j.ejmech.2009.10.020. Epub 2009 Nov 13. Eur J Med Chem. 2010. PMID: 19913952
533 results